Baclofen vs. Klonopin

Are Baclofen and Klonopin the Same Thing?

Baclofen and Klonopin (clonazepam) are muscle relaxants used for treating muscle spasms.

A difference is baclofen is also used to treat muscle clonus, rigidity, and pain caused by multiple sclerosis. Baclofen is also injected into the spinal cord to treat severe spasticity, spinal cord injuries, and other spinal cord diseases.

Klonopin is in a different class of drugs called benzodiazepines, and is usually prescribed for the treatment of anxiety and seizure disorders.

Brand names for baclofen include Gablofen and Lioresal.

What Are Possible Side Effects of Baclofen?

Common side effects of Baclofen include:

What Are Possible Side Effects of Klonopin?

Common side effects of Klonopin include:

What Is Baclofen?

Baclofen (lorazepam) is indicated for the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms.

What Is Klonopin?

Klonopin is a prescription medicine used to treat epilepsy. It is also used to treat panic attacks.


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What Drugs Interact With Baclofen?

Benzodiazepines like Baclofen produce increased CNS (central nervous system) depressant effects when administered with other CNS depressants such as alcohol, barbiturates, antipsychotics, sedative/hypnotics, anxiolytics, antidepressants, narcotic analgesics, sedative antihistamines, anticonvulsants, and anesthetics.

What Drugs Interact With Klonopin?

The CNS-depressant action of the benzodiazepine class of drugs (including Klonopin) may be potentiated by alcohol, narcotics, barbiturates, nonbarbiturate hypnotics, antianxiety agents, the phenothiazines, thioxanthene and butyrophenone classes of antipsychotic agents, monoamine oxidase inhibitors and the tricyclic antidepressants, and by other anticonvulsant drugs.

Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Taking KLONOPIN with certain other medicines can cause side effects or affect how well they work. Do not start or stop other medicines without talking to your healthcare provider.

Know the medicines you take. Keep a list of them and show it to your healthcare provider and pharmacist when you get a new medicine.

How Should Baclofen Be Taken?

Baclofen can be taken with or without food. Baclofen tablets should be swallowed with water.

How Should Klonopin Be Taken?

  • Take Klonopin exactly as your healthcare provider tells you. Klonopin is available as a tablet.
  • Do not stop taking Klonopin without first talking to your healthcare provider. Stopping Klonopin suddenly can cause serious problems.
  • Klonopin tablets should be taken with water and swallowed whole.
  • If you take too much Klonopin, call your healthcare provider or local Poison Control Center right away.


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RxList. Baclofen Prescribing Information.
FDA. Klonopin Drug Information.,020813s009lbl.pdf

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