Bactrim vs. Septra

Reviewed on 2/1/2021

Are Bactrim and Septra the Same Thing?

Bactrim (sulfamethoxazole and trimethoprim) is a combination of two antibiotics and Septra (trimethoprim and sulfamethoxazole) is a quinolone antibiotic. Both drugs are used to treat bacterial infections such as urinary tract infections, bronchitis and other lung infections. Bactrim is also used to treat ear infections (acute otitis media), Shigellosis, Pneumocystis pneumonia, traveler's diarrhea, and methicillin-resistant Staphylococcus aureus (MRSA). Septra is also prescribed to treat infections of the skin, bones, and joints.

What Are Possible Side Effects of Bactrim?

Common side effects of Bactrim include:

Tell your doctor if you experience serious side effects of Bactrim including:

What Are Possible Side Effects of Septra?

Common side effects of Septra include:

  • nausea,
  • vomiting,
  • diarrhea,
  • loss of appetite,
  • painful or swollen tongue,
  • dizziness,
  • spinning sensation,
  • ringing in your ears,
  • tired feeling, or
  • sleep problems (insomnia).

Tell your doctor if you have serious side effects of Septra including:

What is Bactrim?

Bactrim (sulfamethoxazole and trimethoprim) DS is a combination of two antibiotics used to treat urinary tract infections, acute otitis media, bronchitis, Shigellosis, Pneumocystis pneumonia, traveler's diarrhea, methicillin-resistant Staphylococcus aureus (MRSA), and other bacterial infections susceptible to this antibiotic. Bactrim is available as a generic drug.

What is Septra?

Septra (trimethoprim and sulfamethoxazole) is a combination of two antibiotics used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea, methicillin-resistant Staphylococcus aureus (MRSA) and Pneumocystis carinii pneumonia. Septra is available in generic form.

QUESTION

Bowel regularity means a bowel movement every day. See Answer

What Drugs Interact With Bactrim?

Both Bactrim and Septra may interact with blood thinners, cyclosporine, methotrexate, oral diabetes medications, and seizure medications. Bactrim may also interact with antidepressants, digoxin, diuretics (water pills), indomethacin, leucovorin, calcium folinate, and heart or blood pressure medications. Septra may also interact clozapine, probenecid, ropinirole, theophylline, NSAIDs (nonsteroidal anti-inflammatory drugs), or steroids.

What Drugs Interact With Septra?

Septra may interact with seizure medications, diuretics (water pills), blood thinners, methotrexate, or ACE inhibitors. Tell your doctor all medications you use. During pregnancy, Septra should be used only when prescribed. It should not be used near the expected delivery date because of possible harm to the fetus. This drug passes into breast milk. While there have been no reports of harm to healthy infants, this drug may have undesirable effects on infants who are ill or premature or have certain disorders (jaundice, high blood levels of bilirubin, G6PD deficiency). Breastfeeding is not recommended for infants with these conditions. Consult your doctor before breastfeeding.

How Should Bactrim Be Taken?

Administer the solution by intravenous infusion over a period of 60 to 90 minutes. Avoid administration by rapid infusion or bolus injection. Do NOT administer Bactrim intramuscularly.

How Should Septra Be Taken?

The dose of Septra varies depending on the condition being treated.

Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
Dailymed. Bactrim Product Information.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f59d0c04-9c66-4d53-a0e1-cb55570deb62&audience=consumer

Dailymed. Septra Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/017376s060lbl.pdf

Health Solutions From Our Sponsors