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Benadryl vs. Vistaril

Are Benadryl and Vistaril the Same Thing?

Benadryl (diphenhydramine) and Vistaril (hydroxyzine pamoate) are antihistamines used to treat allergic skin reactions such as hives or contact dermatitis.

Benadryl is also used to treat insomnia, motion sickness, and mild cases of Parkinsonism.

Vistaril is also used as a sedative to treat anxiety and tension, or to control nausea and vomiting. Vistaril is also used together with other medications given for anesthesia.

Benadryl is available in generic form and over-the-counter (OTC) while Vistaril is available by prescription.

What Are Possible Side Effects of Benadryl?

Side effects of Benadryl include:

What Are Possible Side Effects of Vistaril?

Common side effects of Vistaril include:

  • dizziness,
  • drowsiness,
  • blurred vision,
  • dry mouth,
  • stomach upset,
  • or headache.
Tell your doctor if you experience serious side effects of Vistaril including:
  • restless muscle movements in your eyes, tongue, jaw, or neck,
  • tremors (uncontrolled shaking),
  • confusion,
  • or seizures (convulsions).

QUESTION

Allergies can best be described as: See Answer

What is Benadryl?

Benadryl (diphenhydramine) is an antihistamine used to treat allergies, hives, insomnia, motion sickness, and mild cases of Parkinsonism.

What is Vistaril?

What is Vistaril?

Vistaril (hydroxyzine pamoate) is an antihistamine with anticholinergic (drying) and sedative properties used as a sedative to treat anxiety and tension. Vistaril is also used together with other medications given for anesthesia. Vistaril may also be used to control nausea and vomiting, or to treat allergic skin reactions such as hives or contact dermatitis.

What Drugs Interact With Benadryl?

Benadryl may interact with other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety).

Benadryl may also interact with monoamine oxidase inhibitors (MAOIs).

What Drugs Interact With Vistaril?

Vistaril may interact with other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety).

SLIDESHOW

Could I Be Allergic? Discover Your Allergy Triggers See Slideshow

How Should Benadryl Be Taken?

A typical dose of Benadryl is 25-50 mg every 4-6 hours. Benadryl may interact with monoamine oxidase inhibitors (MAOIs), other over-the-counter cough, cold, allergy, or insomnia medications, anxiety or sleep medicines, antidepressants, or any other medications that make you feel drowsy, sleepy, or relaxed. Tell your doctor all medications and supplements you use. Benadryl has not been adequately evaluated in pregnant women. Benadryl is secreted in breast milk. Because of the risk of stimulation and seizures in infants, especially newborns and premature infants, antihistamines should not be used by nursing mothers.

How Should Vistaril Be Taken?

The recommended dose of Vistaril for treating itch (pruritus) is 25 mg, 3 or 4 times daily. For sedation, the recommended dose is 50 to 100 mg. The dose to treat anxiety and tension is 50 to 100 mg 4 times daily.

Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
Medical Editor: John P. Cunha, DO, FACOEP

SOURCE:

RxList. Benadryl Medication Guide.

https://www.rxlist.com/benadryl-drug.htm#medguide

RxList. Vistaril Side Effects Drug Center.

https://www.rxlist.com/vistaril-side-effects-drug-center.htm
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