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Benadryl vs. Zyrtec

Are Benadryl and Zyrtec the Same Thing?

Benadryl (diphenhydramine) and Zyrtec (cetirizine hydrochloride) are antihistamines used to treat allergy symptoms, such as itching, hives, runny nose, watery eyes, and sneezing from hay fever (allergic rhinitis) and other allergies, such as allergies to molds and dust mites.

Benadryl is also used to treat insomnia, motion sickness, and mild cases of Parkinsonism.

A main difference between Benadryl and Zyrtec is that Zyrtec tends to cause less drowsiness and sedation than Benadryl.

Both Benadryl and Zyrtec are available in generic form and over-the-counter (OTC).

What Are Possible Side Effects of Benadryl?

Side effects of Benadryl include:

What Are Possible Side Effects of Zyrtec?

Common side effects of Zyrtec include:

In children, side effects of Zyrtec include:

  • stomach pain and
  • vomiting.

The side effect of sleepiness may occur when taking Zyrtec, so do not drive a car or operate potentially dangerous machinery.

QUESTION

Allergies can best be described as: See Answer

What is Benadryl?

Benadryl (diphenhydramine) is an antihistamine used to treat allergies, hives, insomnia, motion sickness, and mild cases of Parkinsonism.

What is Zyrtec?

Zyrtec is medication that temporarily relieves these symptoms due to hay fever or other upper respiratory allergies.

What Drugs Interact With Benadryl?

Benadryl may interact with other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety).

Benadryl may also interact with monoamine oxidase inhibitors (MAOIs).

What Drugs Interact With Zyrtec?

Zyrtec may interact with alcohol, other medicines that make you sleepy (such as other cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety).

SLIDESHOW

Could I Be Allergic? Discover Your Allergy Triggers See Slideshow

How Should Benadryl Be Taken?

A typical dose of Benadryl is 25-50 mg every 4-6 hours. Benadryl may interact with monoamine oxidase inhibitors (MAOIs), other over-the-counter cough, cold, allergy, or insomnia medications, anxiety or sleep medicines, antidepressants, or any other medications that make you feel drowsy, sleepy, or relaxed. Tell your doctor all medications and supplements you use. Benadryl has not been adequately evaluated in pregnant women. Benadryl is secreted in breast milk. Because of the risk of stimulation and seizures in infants, especially newborns and premature infants, antihistamines should not be used by nursing mothers.

How Should Zyrtec Be Taken?

Adults and children 6 years and over should take one 10 mg capsule once daily; do not take more than one 10 mg capsule in 24 hours. A 5 mg product may be appropriate for less severe symptoms.

Adults 65 years of age or older, children under 6 years of age, and consumers with liver or kidney disease should consult a doctor before using this product.

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Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

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You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
Medical Editor: John P. Cunha, DO, FACOEP

SOURCE:

RxList. Benadryl Medication Guide.

https://www.rxlist.com/benadryl-drug.htm#medguide

RxList. Zyrtec Side Effects Drug Center.

https://www.rxlist.com/zyrtec-side-effects-drug-center.htm

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