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Bentyl vs. Linzess

Reviewed on 4/17/2019

Are Bentyl and Linzess the Same Thing?

Bentyl (dicyclomine) and Linzess (linaclotide) are used to treat irritable bowel syndrome (IBS).

Linzess is specifically used to treat irritable bowel syndrome with constipation (IBS-C). Linzess is also used to treat chronic idiopathic constipation (CIC) in adults.

Bentyl and Linzess belong to different drug classes. Bentyl is an anticholinergic and Linzess is a guanylate cyclase-C agonist.

What Are Possible Side Effects of Bentyl?

Common side effects of Bentyl include:

What Are Possible Side Effects of Linzess?

Common side effects of Linzess include:

What is Bentyl?

Bentyl (dicyclomine) is an anticholinergics prescribed for irritable bowel syndrome (IBS).

What is Linzess?

Linzess (linaclotide) is a guanylate cyclase-C agonist used to treat irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC) in adults.

QUESTION

What is irritable bowel syndrome or IBS? See Answer

What Drugs Interact With Bentyl?

Bentyl may interact with amantadine, MAO inhibitors, phenothiazines, or antidepressants.

Bentyl may also interact with other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, or anxiety), digoxin, metoclopramide, atropine, belladonna, benztropine, dimenhydrinate, methscopolamine, scopolamine, bronchodilators, bladder or urinary medications, heart rhythm medications, irritable bowel medications, nitrates, steroids, or ulcer medications.

What Drugs Interact With Linzess?

Linzess may interact with other drugs.

How Should Bentyl Be Taken?

The usual doses of Bentyl range from from 20 - 40 mg given 4 times daily.

How Should Linzess Be Taken?

The recommended dose of Linzess for those with irritable bowel syndrome (IBS) is 290 mcg taken once a day on an empty stomach, at least 30 minutes before the first meal of the day. The same applies for those with chronic idiopathic constipation only the dosage is 145 mcg. Pediatric patients under the age of 17 should not take Linzess.

SLIDESHOW

Digestive Disorders: Common Misconceptions See Slideshow
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References

RxList. Bentyl Medication Guide.
https://www.rxlist.com/bentyl-drug.htm#medguide
RxList. Linzess Medication Guide.
https://www.rxlist.com/linzess-drug.htm#medguide
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