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BenzaClin

Last reviewed on RxList: 3/9/2020
BenzaClin Side Effects Center

What Is BenzaClin?

BenzaClin (clindamycin - benzoyl peroxide) Topical Gel is a combination of two antibacterial drugs indicated for the topical treatment of acne vulgaris. BenzaClin Topical Gel is available in generic form.

What Are Side Effects of BenzaClin?

Side effects of BenzaClin Topical Gel include:

  • dry skin,
  • severe skin redness,
  • burning,
  • itching or tingly feeling,
  • skin peeling,
  • irritation, and
  • stinging.

Tell your doctor if you have serious side effects of BenzaClin Topical Gel including:

  • severe redness,
  • burning,
  • stinging, or
  • peeling of treated skin areas; or
  • diarrhea that is watery or bloody.

Dosage for BenzaClin

BenzaClin Topical Gel has 10mg clindamycin and 50mg benzoyl peroxide strength per gram of gel. Topical clindamycin is absorbed through the skin surface.

What Drugs, Substances, or Supplements Interact with BenzaClin?

BenzaClin Topical Gel may interact with erythromycin topical or oral. Tell your doctor all medications and supplements you use.

BenzaClin During Pregnancy and Breastfeeding

There are no well-controlled trials in pregnant women treated with BenzaClin Topical Gel. It also is not known whether BenzaClin Topical Gel can cause fetal harm when administered to a pregnant woman. It is unknown if BenzaClin Topical Gel passes into breast milk or if it could harm a nursing baby. Breastfeeding while using BenzaClin Topical Gel is not recommended.

Additional Information

Our BenzaClin (clindamycin – benzoyl peroxide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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BenzaClin Consumer Information

Benzoyl peroxide can cause a rare but serious allergic reaction or severe skin irritation. These reactions may occur just a few minutes after you apply the medicine, or within a day or longer afterward.

Stop using this medicine and get emergency medical help if you have signs of an allergic reaction: hives, itching; difficult breathing, feeling light-headed; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • severe redness, burning, stinging, or peeling of treated skin areas; or
  • diarrhea that is watery or bloody.

Common side effects may include:

  • mild burning or stinging;
  • itching or tingly feeling;
  • dryness or peeling of treated skin; or
  • redness or other irritation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for BenzaClin (Clindamycin and Benzoyl Peroxide)

QUESTION

Acne is the result of an allergy. See Answer
BenzaClin Professional Information

SIDE EFFECTS

During clinical trials, the most frequently reported adverse event in the BenzaClin (clindamycin and benzoyl peroxide) treatment group was dry skin (12%). The Table below lists local adverse events reported by at least 1% of patients in the BenzaClin (clindamycin and benzoyl peroxide) and vehicle groups.

Local Adverse Events - all causalities in > /= 1% of patients

  BenzaClin
n = 420
Vehicle
n = 168
Application site reaction 13 (3%) 1 ( < 1%)
Dry skin 50 (12%) 10 (6%)
Pruritus 8 (2%) 1 ( < 1%)
Peeling 9 (2%) -
Erythema 6 (1%) 1 ( < 1%)
Sunburn 5 (1%) -

The actual incidence of dry skin might have been greater were it not for the use of a moisturizer in these studies.

Anaphylaxis, as well as allergic reactions leading to hospitalization, have been reported during post-marketing use of clindamycin/benzoyl peroxide products. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Read the entire FDA prescribing information for BenzaClin (Clindamycin and Benzoyl Peroxide)

Related Resources for BenzaClin

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Read the BenzaClin User Reviews »

© BenzaClin Patient Information is supplied by Cerner Multum, Inc. and BenzaClin Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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