Bethkis vs. Kitabis Pak, Tobi

Are Bethkis and Kitabis, Tobi the Same Thing?

Bethkis (tobramycin) and Kitabis Pak (tobramycin) Inhalation Solution are aminoglycoside antibiotics used to treat cystic fibrosis patients with Pseudomonas aeruginosa.

Side effects of Bethkis and Kitabis Pak that are similar include voice changes, hoarseness, decrease in lung function, and sore throat.

Side effects of Bethkis that are different from Kitabis Pak include wheezing, nosebleed, bronchitis, rales, difficulty speaking, tonsillitis, diarrhea, and increased immunoglobins.

Side effects of Kitabis Pak that are different from Bethkis include increased cough, productive cough, coughing up blood, shortness of breath, altered taste, and rash.

Both Bethkis and Kitabis Pak may interact with furosemide and other drugs that may harm the kidneys, liver, nervous system, or ears.

Bethkis may also interact with ethacrynic acid, urea, and mannitol.

What Are Possible Side Effects of Bethkis?

Common side effects of Bethkis include:

  • changes in the patient's voice
  • hoarseness
  • decrease in lung function
  • wheezing
  • nosebleed
  • sore throat
  • bronchitis
  • rales
  • difficulty speaking
  • tonsillitis
  • diarrhea, and
  • increased immunoglobins

What Are Possible Side Effects of Kitabis, Tobi?

Common side effects of Kitabis include:

  • increased cough
  • sore throat
  • productive cough
  • shortness of breath
  • coughing up blood
  • worsening of lung problems associated with cystic fibrosis
  • changes in your voice (hoarseness)
  • altered taste, and
  • rash

What Is Bethkis?

Bethkis (tobramycin) is an aminoglycoside antibiotic used to treat cystic fibrosis patients with Pseudomonas aeruginosa. Bethkis is available in generic form.

What Is Kitabis, Tobi?

Kitabis Pak (tobramycin) Inhalation Solution is an antibiotic used for the management of cystic fibrosis in adults and pediatric patients 6 years of age and older with P. aeruginosa.


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What Drugs Interact With Bethkis?

Bethkis may interact with Edecrin (ethacrynic acid), Lasix (furosemide), urea, or mannitol. Bethkis should not be taken with drugs known to be toxic to structures within the ears, or drugs known to be toxic to nerves or nerve tissues. Bethkis may harm a fetus if taken while pregnant. Breastfeeding mothers should talk with their doctors to decide where to discontinue drug or continue breastfeeding.

What Drugs Interact With Kitabis, Tobi?

Kitabis Pak may interact with other medicines that may harm your nervous system, kidneys or hearing, or diuretics. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plant o become pregnant before using Kitabis Pak. This drug may harm a fetus. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

How Should Bethkis Be Taken?

Bethkis should be taken twice daily by mouth in repeated cycles of 28 days on, followed by 28 days off.

How Should Kitabis, Tobi Be Taken?

The 300 mg/5mL dose of Kitabis Pak inhalation solution is the same for all patients regardless of age or weight.


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Chiesi. Bethkis Drug Information.

Novartis AG. Kitabis Product Information.

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