Bicillin L-A Inj / Tubex

Last reviewed on RxList: 9/6/2019
Bicillin L-A Inj / Tubex Side Effects Center

Last reviewed on RxList 9/6/2019

Bicillin L-A (penicillin G benzathine) is an antibiotic used to treat or to prevent a variety of bacterial infections. Common side effects of Bicillin L-A include:

  • pain at the injection site,
  • nausea,
  • vomiting,
  • allergic reaction,
  • blurred vision,
  • dizziness, or
  • tired feeling.

Tell your doctor if you have serious side effects of Bicillin L-A including:

  • severe pain or peeling skin at injection site,
  • joint or muscle pain,
  • headache,
  • shortness of breath,
  • dizziness,
  • vision changes,
  • fast/slow/pounding heartbeat,
  • numbness or tingling of arms or legs,
  • pain/redness/swelling of arms or legs,
  • change in skin color near injection site or on arms or legs,
  • uncontrolled movements,
  • inability to move,
  • changes in the amount of urine,
  • new signs of infection (e.g., fever, persistent sore throat),
  • easy bruising or bleeding,
  • extreme tiredness,
  • dark or cloudy urine,
  • seizures, or
  • mental/mood changes (e.g., depression, agitation).

The recommended dosage of Bicillin L-A is based on the patient's weight and the infection being treated. It is administered by deep intramuscular injection only. Bicillin L-A may interact with blood thinners (for example Coumadin [warfarin]), bacterial vaccines, Rheumatrex, Trexall (methotrexate), NSAIDs, propenecid, tetracyclines, diuretics, and others. Tell your doctor all medications you use. Talk to your doctor if you are pregnant or plan on becoming pregnant during treatment. Consult your doctor before using Bicillin L-A if you are breastfeeding.

Our Bicillin L-A (penicillin G benzathine) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

Bowel regularity means a bowel movement every day. See Answer
Bicillin L-A Inj / Tubex Consumer Information

3 pharmacies near 20147 have coupons for Bicillin L-A (Brand Names:Bicillin L-A Injectable in Tubex for 2ML of 1200000UNIT/2ML)

Walgreens
Walgreens
$22.99

Est. Regular Price

$168.68

with free coupon

View Coupon
CVS Pharmacy
CVS Pharmacy
$22.99

Est. Regular Price

$169.4

with free coupon

View Coupon
Costco
Costco
$22.99

Est. Regular Price

$171.09

with free coupon

View Coupon

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Some side effects may occur if the medicine has been accidentally injected near a vein or nerve. Tell your doctor right away if you have:

  • pain, numbness, tingling, burning, or feeling cold;
  • pale or mottled skin, blue-colored lips, fingers, or toes;
  • severe pain, tingling, weakness, or swelling in your lower leg;
  • weakness in your arms or legs; or
  • blistering, peeling, discoloration, or painful skin changes where the medicine was injected.

Also call your doctor at once if you have:

  • severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);
  • a light-headed feeling, like you might pass out;
  • slow heart rate, weak pulse, fainting, slow breathing (breathing may stop);
  • pounding heartbeats or fluttering in your chest;
  • confusion, agitation, hallucinations (seeing or hearing things that aren't real), extreme fear;
  • a seizure;
  • pain, swelling, warmth, redness, bruising, bleeding, or a lump where the medicine was injected;
  • easy bruising or bleeding;
  • pale or yellowed skin, dark colored urine;
  • urination problems; or
  • signs of a new infection--fever, chills, mouth sores, warmth or redness under your skin, vaginal itching or discharge.

Common side effects may include:

  • nausea, vomiting, diarrhea;
  • itching, sweating, allergic reaction;
  • flushing (sudden warmth, redness, or tingly feeling);
  • feeling anxious, nervous, weak, or tired;
  • headache, dizziness, drowsiness;
  • muscle or joint pain; or
  • pain, swelling, bruising, or a hard lump where an injection was given.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Bicillin L-A Inj / Tubex (Penicillin G Benzathine Injectable in Tubex)

SLIDESHOW

Fungal Skin Infections: Types, Symptoms, and Treatments See Slideshow
Bicillin L-A Inj / Tubex Professional Information

SIDE EFFECTS

As with other penicillins, untoward reactions of the sensitivity phenomena are likely to occur, particularly in individuals who have previously demonstrated hypersensitivity to penicillins or in those with a history of allergy, asthma, hay fever, or urticaria.

As with other treatments for syphilis, the Jarisch-Herxheimer reaction has been reported.

The following have been reported with parenteral penicillin G:

General: Hypersensitivity reactions including the following: skin eruptions (maculopapular to exfoliative dermatitis), urticaria, laryngeal edema, fever, eosinophilia; other serum sickness-like reactions (including chills, fever, edema, arthralgia, and prostration); and anaphylaxis including shock and death. Note: Urticaria, other skin rashes, and serum sickness-like reactions may be controlled with antihistamines and, if necessary, systemic corticosteroids. Whenever such reactions occur, penicillin G should be discontinued unless, in the opinion of the physician, the condition being treated is life-threatening and amenable only to therapy with penicillin G. Serious anaphylactic reactions require immediate emergency treatment with epinephrine. Oxygen, intravenous steroids, and airway management, including intubation, should also be administered as indicated.

Gastrointestinal: Pseudomembranous colitis. Onset of pseudomembranous colitis symptoms may occur during or after antibacterial treatment. (See WARNINGS section.)

Hematologic: Hemolytic anemia, leukopenia, thrombocytopenia.

Neurologic: Neuropathy.

Urogenital: Nephropathy.

The following adverse events have been temporally associated with parenteral administration of penicillin G benzathine:

Body as a Whole: Hypersensitivity reactions including allergic vasculitis, pruritus, fatigue, asthenia, and pain; aggravation of existing disorder; headache.

Cardiovascular: Cardiac arrest; hypotension; tachycardia; palpitations; pulmonary hypertension; pulmonary embolism; vasodilation; vasovagal reaction; cerebrovascular accident; syncope.

Gastrointestinal: Nausea, vomiting; blood in stool; intestinal necrosis.

Hemic and Lymphatic: Lymphadenopathy.

Injection Site: Injection site reactions including pain, inflammation, lump, abscess, necrosis, edema, hemorrhage, cellulitis, hypersensitivity, atrophy, ecchymosis, and skin ulcer. Neurovascular reactions including warmth, vasospasm, pallor, mottling, gangrene, numbness of the extremities, cyanosis of the extremities, and neurovascular damage.

Metabolic: Elevated BUN, creatinine, and SGOT.

Musculoskeletal: Joint disorder; periostitis; exacerbation of arthritis; myoglobinuria; rhabdomyolysis.

Nervous System: Nervousness; tremors; dizziness; somnolence; confusion; anxiety; euphoria; transverse myelitis; seizures; coma. A syndrome manifested by a variety of CNS symptoms such as severe agitation with confusion, visual and auditory hallucinations, and a fear of impending death (Hoigne's syndrome), has been reported after administration of penicillin G procaine and, less commonly, after injection of the combination of penicillin G benzathine and penicillin G procaine. Other symptoms associated with this syndrome, such as psychosis, seizures, dizziness, tinnitus, cyanosis, palpitations, tachycardia, and/or abnormal perception in taste, also may occur.

Respiratory: Hypoxia; apnea; dyspnea.

Skin: Diaphoresis.

Special Senses: Blurred vision; blindness.

Urogenital: Neurogenic bladder; hematuria; proteinuria; renal failure; impotence; priapism.

Read the entire FDA prescribing information for Bicillin L-A Inj / Tubex (Penicillin G Benzathine Injectable in Tubex)

© Bicillin L-A Inj / Tubex Patient Information is supplied by Cerner Multum, Inc. and Bicillin L-A Inj / Tubex Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

Health Solutions From Our Sponsors