- Are Boniva and Prolia the Same Thing?
- What Are Possible Side Effects of Boniva?
- What Are Possible Side Effects of Prolia?
- What Is Boniva?
- What Is Prolia?
- What Drugs Interact with Boniva?
- What Drugs Interact with Prolia?
- How Should Boniva Be Taken?
- How Should Prolia Be Taken?
Are Boniva and Prolia the Same Thing?
Prolia (denosumab) and Boniva (ibandronate) are used to prevent and treat bone loss (osteoporosis) in women who are at high risk for bone fracture after menopause.
Prolia and Boniva belong to different drug classes. Prolia is a monoclonal antibody and Boniva is a bisphosphonate.
What Are Possible Side Effects of Boniva?
Common side effects of Boniva include:
- back pain,
- redness or swelling of your eyes,
- flu-like symptoms,
- nausea or stomach upset,
- pain in your arms or legs,
- redness or swelling where Boniva was injected,
- allergic reaction,
- joint pain,
- spinning sensation (vertigo),
- upper respiratory infection,
- pneumonia, or
- urinary tract infection.
What Are Possible Side Effects of Prolia?
Common side effects of Prolia include:
- low calcium levels (especially if you have kidney problems),
- back pain,
- muscle pain,
- pain in your arms and legs,
- diarrhea, or
- skin problems (eczema, blisters, dry skin, peeling, redness, itching, small bumps).
You may also be more likely to get a serious infection, such as a skin, ear, stomach/gut, or bladder infection while taking Prolia. Tell your doctor if you develop signs of infection, such as:
- fever/chills, night sweats,
- red/swollen/tender/warm skin (with or without pus),
- severe stomach or abdominal pain,
- ear pain or drainage, trouble hearing,
- frequent/painful/burning urination, or
- pink/bloody urine.
- severe itching, burning, rask, blistering, peeling, or dryness of the skin,
- shortness of breath,
- pinpoint purple or red spots under your skin,
- flu symptoms, or
- weight loss.
What Is Boniva?
Boniva (ibandronate) is a bisphosphonate drug that alters the cycle of bone formation and breakdown in the body used to treat or prevent osteoporosis in women after menopause. Boniva slows bone loss while increasing bone mass, which may prevent bone fractures.
What Is Prolia?
Prolia (denosumab) is a monoclonal antibody used to treat bone loss (osteoporosis) in women who are at high risk for bone fracture after menopause.
What Drugs Interact With Boniva?
Boniva may interact with aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs).
Boniva may also interact with products containing calcium, aluminum, magnesium, or iron (such as antacids, supplements or vitamins).
What Drugs Interact With Prolia?
Prolia may interact with steroids or cancer medicine, cyclosporine, sirolimus, tacrolimus, basiliximab, muromonab-CD3, mycophenolate mofetil, azathioprine, leflunomide, or etanercept.
Health Solutions From Our Sponsors
All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).
Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.
Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.
The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.
As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.
Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.
If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.
You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.
Genentech. Boniva Product Information.
Amgen. Prolia Product Information.