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Bonsity vs. Fosamax

Reviewed on 10/29/2019

Are Bonsity and Fosamax the Same Thing?

Bonsity (teriparatide injection) and Fosamax (alendronate sodium) are used to treat osteoporosis.

Fosamax is also used to prevent osteoporosis and to treat Paget's disease.

Bonsity and Fosamax belong to different drug classes. Bonsity is a parathyroid hormone analog (PTH 134) and Fosamax is a bisphosphonate.

Side effects of Bonsity and Fosamax that are similar include joint pain, nausea, dizziness, headache, diarrhea, constipation, and heartburn/indigestion.

Side effects of Bonsity that are different from Fosamax include body pain, runny nose, cough, and sore throat.

Side effects of Fosamax that are different from Bonsity include gas, bloating, vomiting, stomach pain, joint swelling, swelling in your hands or feet, eye pain, back pain, and weakness.

Bonsity may interact with digoxin.

Fosamax may interact with aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs).

What Are Possible Side Effects of Bonsity?

Common side effects of Bonsity include:

  • joint pain,
  • body pain,
  • nausea,
  • runny nose,
  • dizziness,
  • headache,
  • diarrhea,
  • constipation,
  • indigestion,
  • cough, and
  • sore throat

What Are Possible Side Effects of Fosamax?

Common side effects of Fosamax include:

  • gas,
  • constipation,
  • heartburn,
  • diarrhea,
  • bloating,
  • nausea,
  • vomiting,
  • stomach pain,
  • joint pain or swelling,
  • swelling in your hands or feet,
  • dizziness,
  • headache,
  • eye pain,
  • back pain, or
  • weakness.

Serious side effects of Fosamax include:

  • severe pain (joints, bone, muscle, jaw, back or heartburn),
  • chest pain,
  • difficulty swallowing,
  • bloody stools,
  • eye pain,
  • skin blisters, and
  • swelling of the face, tongue, or throat.

What Is Bonsity?

Bonsity (teriparatide injection) is a parathyroid hormone analog (PTH 1- 34) indicated for treatment of postmenopausal women with osteoporosis at high risk for fracture; to increase bone mass in men with primary or hypogonadal osteoporosis at high risk for fracture; and for treatment of men and women with osteoporosis associated with sustained systemic glucocorticoid therapy at high risk for fracture.

What Is Fosamax?

Fosamax (alendronate sodium) is a bisphosphonate that is a specific inhibitor of osteoclast-mediated bone resorption used to both treat and prevent osteoporosis, and to treat Paget's disease.

QUESTION

What is another medical term for osteoporosis? See Answer

What Drugs Interact With Bonsity?

Bonsity may interact with digoxin. Tell your doctor all medications and supplements you use. Bonsity is not recommended for use during pregnancy; it is unknown how it would affect a fetus. It is unknown if Bonsity passes into breast milk. Because of a possible potential for osteosarcoma, breastfeeding is not recommended during treatment with Bonsity.

What Drugs Interact With Fosamax?

Fosamax may interact with aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs).

How Should Bonsity Be Taken?

The recommended dose of Bonsity is 20 mcg subcutaneously once a day. Bonsity may interact with digoxin.

How Should Fosamax Be Taken?

Fosamax is available in a tablet or oral liquid form. Each bottle of the oral solution contains 91.35 mg of alendronate monosodium salt trihydrate, which is the molar equivalent to 70 mg of the drug. The recommended initial dosage is one 70 mg molar equivalent tablet or oral liquid bottle once weekly or one 10 mg molar equivalent tablet per day. Fosamax must be taken at least one-half hour before the first food, beverage, or medication of the day with plain water only to avoid any reduction in gastrointestinal adsorption.

SLIDESHOW

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References
FDA. Bonsity Drug Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/211939s000lbl.pdf

Merck. Fosamax Product Information.

https://www.merck.com/product/usa/pi_circulars/f/fosamax/fosamax_onceweekly_ppi.pdf

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