Bonsity vs. Reclast

Reviewed on 10/29/2019

Are Bonsity and Reclast the Same Thing?

Bonsity (teriparatide injection) and Reclast (zoledronic acid) are used to treat postmenopausal women with osteoporosis at high risk for fracture; to increase bone mass in men with primary or hypogonadal osteoporosis at high risk for fracture; and for treatment of men and women with osteoporosis associated with sustained systemic glucocorticoid therapy at high risk for fracture.

Reclast is also used to treat Paget's disease, high blood levels of calcium caused by cancer (hypercalcemia of malignancy, and multiple myeloma (a type of bone marrow cancer) or cancer that has spread from elsewhere in the body to the bone.

Bonsity and Reclast belong to different drug classes. Bonsity is a parathyroid hormone analog (PTH 134) and Reclast is a bisphosphonate.

Side effects of Bonsity and Reclast that are similar include joint pain, nausea, dizziness, headache, diarrhea, constipation, and cough.

Side effects of Bonsity that are different from Reclast include body pain, runny nose, indigestion, and sore throat.

Side effects of Reclast that are different from Bonsity include tiredness, flu-like symptoms (e.g., fever, chills, muscle/joint aches), vision problems, muscle pain, and injection site reactions (pain, redness, swelling).

Bonsity may interact with digoxin.

Reclast may interact with diuretics (water pills), antibiotics, other medicines that can harm your kidneys, cancer medicines, and nonsteroidal anti-inflammatory drugs (NSAIDs).

What Are Possible Side Effects of Bonsity?

Common side effects of Bonsity include:

  • joint pain,
  • body pain,
  • nausea,
  • runny nose,
  • dizziness,
  • headache,
  • diarrhea,
  • constipation,
  • indigestion,
  • cough, and
  • sore throat

What Are Possible Side Effects of Reclast?

Common side effects of Reclast include:

  • nausea,
  • tiredness,
  • flu-like symptoms (e.g., fever, chills, muscle/joint aches),
  • cough,
  • dizziness,
  • headache,
  • vision problems,
  • diarrhea,
  • constipation,
  • joint or muscle pain, or
  • injection site reactions (pain, redness, swelling).

What Is Bonsity?

Bonsity (teriparatide injection) is a parathyroid hormone analog (PTH 1- 34) indicated for treatment of postmenopausal women with osteoporosis at high risk for fracture; to increase bone mass in men with primary or hypogonadal osteoporosis at high risk for fracture; and for treatment of men and women with osteoporosis associated with sustained systemic glucocorticoid therapy at high risk for fracture.

What Is Reclast?

Reclast is a prescription medicine used to:

  • Treat or prevent osteoporosis in women after menopause. Reclast helps reduce the chance of having a hip or spinal fracture (break).
  • Increase bone mass in men with osteoporosis.
  • Treat or prevent osteoporosis in either men or women who will be taking corticosteroid medicines for at least one year.
  • Treat certain men and women who have Paget's disease of the bone.

It is not known how long Reclast works for the treatment and prevention of osteoporosis. You should see your doctor regularly to determine if Reclast is still right for you.

Reclast is not for use in children.

QUESTION

What is another medical term for osteoporosis? See Answer

What Drugs Interact With Bonsity?

Bonsity may interact with digoxin. Tell your doctor all medications and supplements you use. Bonsity is not recommended for use during pregnancy; it is unknown how it would affect a fetus. It is unknown if Bonsity passes into breast milk. Because of a possible potential for osteosarcoma, breastfeeding is not recommended during treatment with Bonsity.

What Drugs Interact With Reclast?

Reclast may interact with different drugs. Reclast may interact with diuretics (water pills), antibiotics, other medicines that can harm your kidneys, cancer medicines, or nonsteroidal anti-inflammatory drugs (NSAIDs).

How Should Bonsity Be Taken?

The recommended dose of Bonsity is 20 mcg subcutaneously once a day. Bonsity may interact with digoxin.

How Should Reclast Be Taken?

  • Your doctor will tell you how often you will receive Reclast.
  • Reclast is given by infusion into your vein (intravenously). Your infusion should last at least 15 minutes.
  • Before you receive Reclast, drink at least 2 glasses of fluid (such as water) within a few hours as directed by your doctor.
  • You may eat before your treatment with Reclast.
  • If you miss a dose of Reclast, call your doctor or healthcare provider to schedule your next dose.

SLIDESHOW

Osteoporosis Super-Foods for Strong Bones With Pictures See Slideshow
Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
FDA. Bonsity Drug Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/211939s000lbl.pdf

Novartis. Reclast Product Information.

https://www.pharma.us.novartis.com/sites/www.pharma.us.novartis.com/files/reclast.pdf?

Health Solutions From Our Sponsors