Bornholm disease: A viral infection that is most commonly caused by an enterovirus called Coxsackie B. Symptoms include fever, intense abdominal and chest pain, and headache. The chest pain is caused by inflammation of the tissue lining the lungs, and it is typically worsened by breathing or coughing. The illness usually lasts from 3 to 14 days. Also known as epidemic myalgia and pleurodynia.