Botox vs. Xeomin

Are Botox and Xeomin the Same Thing?

Botox (onabotulinumtoxinA) and Xeomin (incobotulinumtoxinA) are injectable neuro-toxins used to treat cervical dystonia (severe muscle spasms in the neck), strabismus (crossed eyes), and blepharospasm (eyelid twitching).

Botox is also used to treat chronic migraines, limb spasticity, and axillary hyperhidrosis (sweaty underarms).

What Are Possible Side Effects of Botox?

Common side effects of Botox include:

Drooping of the eyelid (ptosis), inflammation of the cornea (keratitis), eye dryness, itchy eyes, double vision, eye irritation, tearing, increased sensitivity to light, reduced blinking, and eyelid swelling or bruising may occur when used for treating blepharospasm.

What Are Possible Side Effects of Xeomin?

Common side effects of Xeomin include:

  • neck pain
  • dry eyes
  • headache
  • tired feeling
  • diarrhea
  • eyelid swelling or bruising
  • blinking less than usual
  • pain, redness, or swelling where the injection was given

What is Botox?

Botox (onabotulinumtoxinA) is an injectable neuro-toxin used for the treatment of chronic migraines, limb spasticity, axillary hyperhidrosis, cervical dystonia, strabismus, and blepharospasm.

What is Xeomin?

Xeomin (incobotulinumtoxinA) is botulinum toxin type A used to treat cervical dystonia (severe spasms in the neck muscles), and also to treat certain eye muscle conditions caused by nerve disorders. This includes uncontrolled blinking or spasm of the eyelids, and a condition in which the eyes do not point in the same direction.


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What Drugs Interact With Botox?

Administration of botulinum toxin with other agents (for example, aminoglycosides, curare) that affect neuromuscular function may increase the effect of botulinum toxin.

What Drugs Interact With Xeomin?

Xeomin may interact with cold or allergy medicines, muscle relaxers, sleeping pills, bronchodilators, bladder or urinary medicines, irritable bowel medicines, blood thinners, or injected antibiotics. Tell your doctor all medications and supplements you use.

How Should Botox Be Taken?

Botox is administered by injection and dosing depends on the condition that it is used for.

How Should Xeomin Be Taken?

The recommended initial total dose of Xeomin for cervical dystonia is 120 Units.


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Allergan. Botox Cosmetic Product Monograph.

Merz Aesthetics. Xeomin Product Monograph.

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