Brilinta vs. Coumadin

Reviewed on 4/8/2021

Are Brilinta and Coumadin the Same Thing?

Brilinta (ticagrelor) and Coumadin (warfarin) are blood-thinners used to reduce cardiovascular death and heart attack in patients with acute coronary syndromes (ACS).

Side effects of Brilinta and Coumadin that are similar include bruising, bleeding more easily, and nausea.

Side effects of Brilinta that are different from Coumadin include nosebleeds, headache, dizziness, cough, diarrhea, irregular heartbeat, high blood pressure, back pain, low blood pressure, fatigue, and chest pain.

Side effects of Coumadin that are different from Brilinta include vomiting stomach pain, bloating, gas, and altered sense of taste.

Both Brilinta and Coumadin may interact with other medications to prevent blood clots, seizure medicines, antifungal medicines, and tuberculosis medicines.

Brilinta may also interact with antiviral medicines to treat HIV or AIDS, cholesterol medications, heart or blood pressure medications, and opioid medications.

Coumadin may also interact with antibiotics, sulfa drugs, antidepressants, herbal (botanical) products (including coenzyme Q10, cranberry, echinacea, garlic, ginkgo biloba, ginseng, goldenseal, or St. John's wort), secobarbital, and barbiturates.

What Are Possible Side Effects of Brilinta?

Common side effects of Brilinta are related to bleeding and include increased bleeding, nosebleeds, and bruising.

Other side effects of Brilinta include:

  • dizziness,
  • cough,
  • nausea,
  • diarrhea,
  • irregular heartbeat,
  • high or low blood pressure,
  • back pain,
  • fatigue, and
  • chest pain

What Are Possible Side Effects of Coumadin?

Common side effects of Coumadin include:

  • easy bruising and bleeding,
  • nausea, vomiting,
  • stomach pain,
  • bloating,
  • gas, or
  • altered sense of taste

SLIDESHOW

Heart Disease: Symptoms, Signs, and Causes See Slideshow

What Is Brilinta?

Brilinta is a prescription medicine used to treat people who have had a heart attack or severe chest pain that happened because their heart was not getting enough oxygen.

Brilinta is used to lower your chance of having a heart attack or dying from a heart attack or stroke but Brilinta (and similar drugs) can cause bleeding that can be serious and sometimes lead to death.

What Is Coumadin?

Coumadin is prescription medicine used to treat blood clots and to lower the chance of blood clots forming in your body. Blood clots can cause a stroke, heart attack, or other serious conditions if they form in the legs or lungs.

It is not known if Coumadin is safe and effective in children.

What Drugs Interact With Brilinta?

Brilinta may interact with other blood thinners, HIV or AIDS medications, seizure medications, and antifungals. Brilinta may also interact with dexamethasone, digoxin, nefazodone, antibiotics, cholesterol-lowering medications, and heart or blood pressure medications.

Brilinta may also interact with dexamethasone (Decadron), digoxin (Lanoxin, Digitek, Digibind), nefazodone (Serzone), certain antibiotics, cholesterol-lowering medications (statins), and heart or blood pressure medications.

What Drugs Interact With Coumadin?

Coumadin may interact with antibiotics, St. John's wort, aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs), and antifungal medications.

Coumadin may also interact with other medications to prevent blood clots, sulfa drugs, medicines to treat tuberculosis, antidepressants, herbal (botanical) products (including coenzyme Q10, cranberry, echinacea, garlic, ginkgo biloba, ginseng, or goldenseal), secobarbital, barbiturates, and seizure medications.

How Should Brilinta be Taken?

Brilinta can be taken with or without food.

Brilinta is taken with aspirin. Talk to your doctor about the dose of aspirin that you should take with Brilinta. You should not take a dose of aspirin higher than 100 mg daily because it can affect how well Brilinta works. Do not take doses of aspirin higher than what your doctor tells you to take. Tell your doctor if you take other medicines that contain aspirin, and do not take new over-the-counter medicines with aspirin in them.

How Should Coumadin be Taken?

  • Take Coumadin exactly as prescribed. Your healthcare provider will adjust your dose from time to time depending on your response to Coumadin.
  • You must have regular blood tests and visits with your healthcare provider to monitor your condition.
  • If you miss a dose of Coumadin, call your healthcare provider. Take the dose as soon as possible on the same day. Do not take a double dose of Coumadin the next day to make up for a missed dose.
    • Call your healthcare provider right away if you:
    • take too much Coumadin
    • are sick with diarrhea, an infection, or have a fever
    • fall or injure yourself, especially if you hit your head. Your healthcare provider may need to check you

IMAGES

See Images
Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
FDA. Brilinta Drug Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/022433s015lbl.pdf

FDA. Coumadin Drug Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/009218s107lbl.pdf

Health Solutions From Our Sponsors