Brintellix (Trintellix) vs. Effexor

Are Brintellix (Trintellix) and Effexor the Same Thing?

Brintellix (Trintellix) (vortioxetine) and Effexor (venlafaxine) are antidepressants used to treat major depressive disorder (MDD).

The brand name Brintellix (Trintellix) was changed to Trintellix in June 2016 because of confusion with the name of an antiplatelet drug called Brilinta (ticagrelor).

What Are Possible Side Effects of Brintellix (Trintellix)?

Common side effects of Brintellix (Trintellix) include:

What Are Possible Side Effects of Effexor?

Common side effects of Effexor include:

What Is Brintellix (Trintellix)?

Brintellix (vortioxetine) is an antidepressant used to treat major depressive disorder (MDD).

What Is Effexor?

Effexor is a prescription medicine used to treat depression. It is important to talk with your healthcare provider about the risks of treating depression and also the risks of not treating it. You should discuss all treatment choices with your healthcare provider. Talk to your healthcare provider if you do not think that your condition is getting better with Effexor.


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What Drugs Interact With Brintellix (Trintellix)?

Brintellix may interact with monoamine oxidase inhibitors (MAOIs), SSRIs, SNRIs, triptans, buspirone, tramadol, tryptophan, bupropion, fluoxetine, paroxetine, quinidine, rifampicin, carbamazepine, or phenytoin. Tell your doctor all medications and supplements you use. Tell your doctor if you become pregnant or intend to become pregnant during therapy with Brintellix.

What Drugs Interact With Effexor?

Before starting Effexor, USP, tell your healthcare provider if you:

How Should Brintellix (Trintellix) Be Taken?

The recommended starting dose of Brintellix is 10 mg taken orally once daily.

How Should Effexor Be Taken?

  • Take venlafaxine tablets, USP exactly as prescribed. Your healthcare provider may need to change the dose of venlafaxine tablets, USP until it is the right dose for you.
  • Venlafaxine tablets, USP is to be taken with food.
  • If you miss a dose of venlafaxine tablets, USP, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of venlafaxine tablets, USP at the same time.
  • If you take too much venlafaxine tablets, USP, call your healthcare provider or poison control center right away, or get emergency treatment.
  • When switching from another antidepressant to venlafaxine tablets, USP your doctor may want to lower the dose of the initial antidepressant first to avoid side effects


Depression is a(n) __________ . See Answer

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Medical Editor: John P. Cunha, DO, FACOEP

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