Brintellix (Trintellix) vs. Viibryd

Are Brintellix (Trintellix) and Viibryd the Same Thing?

Brintellix (vortioxetine) and Viibryd (vilazodone hydrochloride) are antidepressants used to treat major depressive disorder (MDD).

The brand name Brintellix was changed to Trintellix in June 2016 because of confusion with the name of an antiplatelet drug called Brilinta (ticagrelor).

What Are Possible Side Effects of Brintellix (Trintellix)?

Common side effects of Brintellix (Trintellix) include:

What Are Possible Side Effects of Viibryd?

Common side effects of Viibryd include:

Contact your doctor if you have serious side effects of Viibryd including:

  • easy bruising,
  • unusual bleeding (nose, mouth, vagina, or rectum),
  • blood in your urine or stools,
  • purple or red pinpoint spots under your skin,
  • agitation,
  • hallucinations,
  • fever,
  • loss of coordination,
  • fainting,
  • overactive reflexes,
  • very stiff (rigid) muscles,
  • sweating,
  • confusion,
  • fast or uneven heartbeats,
  • tremors,
  • lightheadedness,
  • racing thoughts,
  • risk-taking behavior,
  • decreased inhibitions,
  • feelings of extreme happiness or sadness,
  • extreme thirst with headache,
  • weakness,
  • trouble concentrating,
  • memory problems,
  • confusion,
  • seizures (convulsions), or
  • shallow breathing.

What Is Brintellix (Trintellix)?

Brintellix (vortioxetine) is an antidepressant used to treat major depressive disorder (MDD).

What Is Viibryd?

Viibryd is a prescription medicine used to treat a certain type of depression called Major Depressive Disorder (MDD). It is important to talk with your healthcare provider about the risks of treating depression and also the risk of not treating it. You should discuss all treatment choices with your healthcare provider. Talk to your healthcare provider if you do not think that your condition is getting better with Viibryd treatment.

It is not known if Viibryd is safe and effective in children.


Depression is a(n) __________ . See Answer

What Drugs Interact With Brintellix (Trintellix)?

Brintellix may interact with monoamine oxidase inhibitors (MAOIs), SSRIs, SNRIs, triptans, buspirone, tramadol, tryptophan, bupropion, fluoxetine, paroxetine, quinidine, rifampicin, carbamazepine, or phenytoin. Tell your doctor all medications and supplements you use. Tell your doctor if you become pregnant or intend to become pregnant during therapy with Brintellix.

What Drugs Interact With Viibryd?

Especially tell your healthcare provider if you take:

Your healthcare provider or pharmacist can tell you if it is safe to take Viibryd with your other medicines. Do not start or stop any medicine while taking Viibryd without talking to your healthcare provider first.

How Should Brintellix (Trintellix) Be Taken?

The recommended starting dose of Brintellix is 10 mg taken orally once daily.

How Should Viibryd Be Taken?

Take Viibryd exactly as prescribed. Your healthcare provider may need to change the dose of Viibryd until it is the right dose for you.

Take Viibryd exactly as prescribed. Your healthcare provider may need to change the dose of Viibryd until it is the right dose for you.

  • Take Viibryd with food. Viibryd may not work as well if you take it on an empty stomach.
  • If you miss a dose of Viibryd, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Viibryd at the same time.
  • If you take too much Viibryd, call your healthcare provider or poison control center at 1-800-222-1222 right away, or get emergency treatment.


Learn to Spot Depression: Symptoms, Warning Signs, Medication See Slideshow

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Medical Editor: John P. Cunha, DO, FACOEP

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