Last updated on RxList: 4/12/2021
Bryhali Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Bryhali?

Bryhali (halobetasol propionate) Lotion is a corticosteroid indicated for the topical treatment of plaque psoriasis in adults.

What Are Side Effects of Bryhali?

Common side effects of Bryhali include:

Dosage for Bryhali

Apply a thin layer dose of Bryhali Lotion to the affected areas once daily.

What Drugs, Substances, or Supplements Interact with Bryhali?

Treatment beyond 8 weeks is not recommended.

Bryhali During Pregnancy and Breastfeeding

Bryhali may interact with other drugs. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Bryhali; it is unknown how it would affect a fetus. It is unknown if Bryhali passes into breast milk. Systemically administered corticosteroids pass into breast milk and could cause adverse effects. It is unknown if topical administration of corticosteroids such as Bryhali could cause unwanted effects in nursing infants. Consult your doctor before breastfeeding.

Additional Information

Our Bryhali (halobetasol propionate) Lotion, for Topical Use Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Types of Psoriasis: Medical Pictures and Treatments See Slideshow
Bryhali Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • worsening of your skin condition;
  • redness, warmth, swelling, oozing, or severe irritation of any treated skin;
  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or
  • possible signs of absorbing this medicine through your skin--weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes.

Common side effects may include:

  • burning, stinging, itching, or dryness of treated skin;
  • pain where the foam was applied;
  • redness or crusting around your hair follicles;
  • stretch marks;
  • spider veins;
  • headache; or
  • cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Bryhali (Halobetasol Propionate Lotion)


Psoriasis causes the top layer of skin cells to become inflamed and grow too quickly and flake off. See Answer
Bryhali Professional Information


Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.

In randomized, double-blind, multicenter, vehicle-controlled clinical trials, 426 adults with plaque psoriasis were treated with BRYHALI Lotion and had post-baseline safety data. Subjects applied BRYHALI Lotion once daily for up to 8 weeks. Table 1 presents adverse reactions that occurred in at least 1% of subjects treated with BRYHALI Lotion and more frequently than in vehicle-treated subjects.

Table 1: Adverse Reactions Occurring in ≥1% of the Subjects Treated with BRYHALI Lotion through Week 8

Vehicle Lotion
Adverse Reaction % %
Upper Respiratory Tract Infection 2% 1%
Application Site Dermatitis 1% 0
Hyperglycemia 1% 0


No Information provided

Read the entire FDA prescribing information for Bryhali (Halobetasol Propionate Lotion)

© Bryhali Patient Information is supplied by Cerner Multum, Inc. and Bryhali Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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