Buprenex vs. ReVia

Are Buprenex and ReVia the Same Thing?

Buprenex (buprenorphine hydrochloride) and ReVia (naltrexone) are narcotic drugs used for different purposes.

Buprenex is indicated for the relief of moderate to severe pain.

ReVia is a special type of narcotic drug that blocks the effects of other narcotic medicines and alcohol used to treat narcotic drug or alcohol addiction.

What Are Possible Side Effects of Buprenex?

Common side effects of Buprenex include:

Tell your doctor if you have serious side effects of Buprenex including:

  • weak or shallow breathing,
  • lightheadedness,
  • fainting,
  • blue lips or fingernails,
  • confusion,
  • feelings of extreme happiness,
  • fast or slow heart rate, or
  • urinating less than usual or not at all.

What Are Possible Side Effects of ReVia?

Common side effects of ReVia include:

Sudden opiate withdrawal symptoms can occur within minutes after taking Revia. Tell your doctor if you have withdrawal symptoms of Revia including:

  • abdominal cramps,
  • nausea or vomiting,
  • diarrhea,
  • joint/bone/muscle aches,
  • mental/mood changes (e.g., anxiety, confusion, extreme sleepiness, visual hallucinations), or
  • runny nose.

What Is Buprenex?

Buprenex (buprenorphine hydrochloride) injectable is a narcotic drug indicated for the relief of moderate to severe pain.

What Is ReVia?

Revia (naltrexone) is a special narcotic drug that blocks the effects of other narcotic medicines and alcohol used to treat narcotic drug or alcohol addiction and is taken orally in tablet form.


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What Drugs Interact With Buprenex?

Buprenex may interact with alcohol, other narcotic pain medications, sedatives, tranquilizers, sleeping pills, muscle relaxers, other medicines that can make you sleepy or slow your breathing, dexamethasone, imatinib, isoniazid, nefazodone, St. John's wort, antibiotics, antifungal medications, barbiturates, blood thinners, heart or blood pressure medications, HIV/AIDS medicines, MAO inhibitors, medicines to treat narcolepsy, phenothiazines, or seizure medications. Tell your doctor all medications and supplements you use.

What Drugs Interact With ReVia?

Revia may interact with narcotic drugs or alcohol, or prescription or over-the-counter medicines to treat a cold, cough, diarrhea, or pain. Tell your doctor all medications and supplements you use.

How Should Buprenex Be Taken?

The usual dosage for persons 13 years of age and over is 1 ml Buprenex given by deep intramuscular or slow (over at least 2 minutes) intravenous injection at up to 6-hour intervals, as needed.

How Should ReVia Be Taken?

To treat alcoholism, a dose of 50 mg Revia once daily is recommended for most patients. To treat opiod dependence, the initial dose of Revia is 25 mg.


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DailyMed. Buprenex Product Information.
FDA. Revia Product Information.

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