Buspar

Last updated on RxList: 07/12/2021
Buspar Patient Information Including Side Effects

Brand Names: BuSpar, BuSpar Dividose, Vanspar

Generic Name: buspirone

What is buspirone (BuSpar, BuSpar Dividose, Vanspar)?

Buspirone is used to treat symptoms of anxiety, such as fear, tension, irritability, dizziness, pounding heartbeat, and other physical symptoms.

Buspirone is not an anti-psychotic medication and should not be used in place of medication prescribed by your doctor for mental illness.

Buspirone may also be used for purposes not listed in this medication guide.

What are the possible side effects of buspirone (BuSpar, BuSpar Dividose, Vanspar)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • chest pain;
  • shortness of breath; or
  • a light-headed feeling, like you might pass out.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Common side effects may include:

  • headache;
  • dizziness, feeling light-headed;
  • nausea; or
  • feeling nervous or excited.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about buspirone (BuSpar, BuSpar Dividose, Vanspar)?

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

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Buspar Patient Information including How Should I Take

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What should I discuss with my healthcare provider before taking buspirone (BuSpar, BuSpar Dividose, Vanspar)?

You should not use buspirone if you are allergic to it.

Do not use buspirone if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

You may need to wait 14 days after stopping buspirone before you can take an MAOI.

Tell your doctor if you have ever had:

Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. These medicines may interact with buspirone and cause a serious condition called serotonin syndrome.

Tell your doctor if you are pregnant.

You should not breastfeed while using buspirone.

Do not give this medicine to a child without medical advice.

How should I take buspirone (BuSpar, BuSpar Dividose, Vanspar)?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You may take buspirone with or without food but take it the same way each time.

If you have switched to buspirone from another anxiety medication, you may need to slowly decrease your dose of the other medication rather than stopping suddenly. Some anxiety medications can cause withdrawal symptoms when you stop taking them suddenly after long-term use.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Some buspirone tablets are scored so you can break the tablet into 2 or 3 pieces in order to take a smaller dose. Do not use a buspirone tablet if it has not been broken correctly and the piece is too big or too small. Follow your doctor's instructions about how much of the tablet to take.

Buspirone can cause false positive results with certain medical tests. You may need to stop using the medicine for at least 48 hours before your test. Tell any doctor who treats you that you are using buspirone.

Store at room temperature away from moisture, heat, and light.

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Buspar Patient Information including If I Miss a Dose

What happens if I miss a dose (BuSpar, BuSpar Dividose, Vanspar)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose (BuSpar, BuSpar Dividose, Vanspar)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking buspirone (BuSpar, BuSpar Dividose, Vanspar)?

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Drinking alcohol may increase certain side effects of buspirone.

Grapefruit may interact with buspirone and lead to unwanted side effects. Avoid the use of grapefruit products.

What other drugs will affect buspirone (BuSpar, BuSpar Dividose, Vanspar)?

Using buspirone with other drugs that make you drowsy or slow your breathing can worsen these effects. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Tell your doctor about all your current medicines. Many drugs can affect buspirone, especially:

  • nefazodone;
  • St. John's wort;
  • an antibiotic--clarithromycin, erythromycin, rifabutin, rifampin, rifapentine, telithromycin;
  • antifungal medicine--itraconazole, ketoconazole;
  • antiviral medicine to treat HIV/AIDS--efavirenz, indinavir, nelfinavir, nevirapine, ritonavir, saquinavir;
  • cancer medicine--apalutamide, enzalutamide, mitotane;
  • heart or blood pressure medicines--diltiazem, verapamil;
  • seizure medicine--carbamazepine, oxcarbazepine, phenytoin, primidone; or
  • steroid medicine--dexamethasone, prednisone.

This list is not complete and many other drugs may affect buspirone. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information (BuSpar, BuSpar Dividose, Vanspar)?

Your pharmacist can provide more information about buspirone.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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