Slideshows Images Quizzes

Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. See additional information.

Cajeput Oil

What other names is Cajeput Oil known by?

Aceite de Cajeput, Cajeputi Aetheroleum, Cajeputier, Essence de Caia-Pouti, Essence de Cajeput, Huile de Cajoupouli, Huile de Cajeput, Kajuput, Kajuputi leucadendra, Kayaputi, Melaleuca leucadendra, Melaleuca Leucodendron, Melaleuca quinquenervia, Myrtus leucadendra, Paperbark Tree Oil, Punk Tree.

What is Cajeput Oil?

Cajeput oil is produced by steam distillation of fresh leaves and twigs of the cajeput tree (Melaleuca leucadendra) and the paperbark tree (Melaleuca quinquenervia). Don't confuse cajeput oil with tea tree oil (Melaleuca alternifolia) or niauli oil (Melaleuca viridiflora).

Cajeput oil is used to treat colds, headaches, toothache, and tumors; to loosen phlegm so it can be coughed up (as an expectorant); and as a tonic.

Some people apply cajeput oil to the skin for mites (scabies) and a fungal infection of the skin (tinea versicolor).

Cajeput oil is also used either alone or in combination with other ingredients in commercially available antiseptic lotions to treat joint pain (rheumatism) and other pains.

Some people inhale cajeput oil as an expectorant.

In dentistry, cajeput oil is used to relieve gum pain after a tooth is removed or lost.

In food and beverages, cajeput oil is used as a flavoring in very small amounts.

Insufficient Evidence to Rate Effectiveness for...

  • Toothache.
  • Colds.
  • Headaches.
  • Tumors.
  • Use as a tonic.
  • Thinning mucous (congestion) and making it easier to cough up, when taken by mouth or inhaled.
  • Fungal skin infections, when applied to the skin.
  • Joint pain (rheumatism), when applied to the skin.
  • Other conditions.
More evidence is needed to rate the effectiveness of cajeput oil for these uses.

SLIDESHOW

Vitamin D Deficiency: How Much Vitamin D Is Enough? See Slideshow

How does Cajeput Oil work?

Cajeput oil contains a chemical called cineole. When applied to the skin, cineole can cause surface warmth and irritation, which relieves pain beneath the skin.

Are there safety concerns?

Very small amounts of cajeput oil are LIKELY SAFE when added to food as flavoring, but the safety of taking larger amounts by mouth is unknown.

Cajeput oil is POSSIBLY SAFE for most people when applied in medicinal amounts to unbroken skin, but it can cause allergic reactions.

It is POSSIBLY UNSAFE to inhale cajeput oil. It can cause breathing problems.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking cajeput oil if you are pregnant or breast-feeding. Stay on the safe side and avoid use.

Children: Cajeput oil is LIKELY UNSAFE when inhaled or applied to the faces of children. It can cause serious breathing problems.

Asthma: Inhaling cajeput oil might cause an asthma attack.

Are there any interactions with medications?


Medications changed by the liver (Cytochrome P450 2D6 (CYP2D6) substrates)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Some medications are changed and broken down by the liver. Cajeput oil might slow down how quickly the liver breaks down some medications. Taking cajeput oil along with some medications that are broken down by the liver might increase the effects and side effects of some medications. Before taking cajeput oil, talk to your healthcare provider if you are taking any medications that are changed by the liver.

Medications that might be affected include amitriptyline (Elavil), clozapine (Clozaril), codeine, desipramine (Norpramin), donepezil (Aricept), fentanyl (Duragesic), flecainide (Tambocor), fluoxetine (Prozac), meperidine (Demerol), methadone (Dolophine), metoprolol (Lopressor, Toprol XL), olanzapine (Zyprexa), ondansetron (Zofran), tramadol (Ultram), trazodone (Desyrel), and others.

Dosing considerations for Cajeput Oil.

The appropriate dose of cajeput oil for use as treatment depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for cajeput oil. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Health Solutions From Our Sponsors

Reviewed on 9/17/2019
References

Amer, A. and Mehlhorn, H. Repellency effect of forty-one essential oils against Aedes, Anopheles, and Culex mosquitoes. Parasitol.Res 2006;99(4):478-490. View abstract.

Bhamarapravati, S., Pendland, S. L., and Mahady, G. B. Extracts of spice and food plants from Thai traditional medicine inhibit the growth of the human carcinogen Helicobacter pylori. In Vivo 2003;17(6):541-544. View abstract.

El Toumy, S. A., Marzouk, M. S., Moharram, F. A., and Aboutabl, E. A. Flavonoids of Melaleuca quinquenervia. Pharmazie 2001;56(1):94-95. View abstract.

Hiermann, A. and Bucar, F. Influence of some traditional medicinal plants of Senegal on prostaglandin biosynthesis. J Ethnopharmacol 1994;42(2):111-116. View abstract.

Jedlickova, Z., Mottl, O., and Sery, V. Antibacterial properties of the Vietnamese cajeput oil and ocimum oil in combination with antibacterial agents. J Hyg Epidemiol.Microbiol.Immunol 1992;36(3):303-309. View abstract.

Lee, C. K. A New Norlupene from the Leaves of Melaleuca leucadendron. J Nat Prod. 3-27-1998;61(3):375-376. View abstract.

Lee, C. K. and Chang, M. H. Four new triterpenes from the heartwood of melaleuca leucadendron. J Nat Prod. 1999;62(7):1003-1005. View abstract.

Lee, T. H., Wang, G. J., Lee, C. K., Kuo, Y. H., and Chou, C. H. Inhibitory effects of glycosides from the leaves of Melaleuca quinquenervia on vascular contraction of rats. Planta Med 2002;68(6):492-496. View abstract.

LOCKHART, C., AUSTIN, D. F., and AUMEN, N. G. Water Level Effects on Growth of Melaleuca Seedlings from Lake Okeechobee (Florida, USA) Littoral Zone. Environ.Manage. 1999;23(4):507-518. View abstract.

Moharram, F. A., Marzouk, M. S., El Toumy, S. A., Ahmed, A. A., and Aboutabl, E. A. Polyphenols of Melaleuca quinquenervia leaves--pharmacological studies of grandinin. Phytother Res 2003;17(7):767-773. View abstract.

Mueller, R. S., Bettenay, S. V., and Tideman, L. Aero-allergens in canine atopic dermatitis in southeastern Australia based on 1000 intradermal skin tests. Aust Vet.J 2000;78(6):392-399. View abstract.

Muller, J. F., Hawker, D. W., McLachlan, M. S., and Connell, D. W. PAHs, PCDD/Fs, PCBs and HCB in leaves from Brisbane, Australia. Chemosphere 2001;43(4-7):507-515. View abstract.

Nawawi, A., Nakamura, N., Hattori, M., Kurokawa, M., and Shiraki, K. Inhibitory effects of Indonesian medicinal plants on the infection of herpes simplex virus type 1. Phytother Res 1999;13(1):37-41. View abstract.

Oelrichs, P. B., MacLeod, J. K., Seawright, A. A., and Grace, P. B. Isolation and identification of the toxic peptides from Lophyrotoma zonalis (Pergidae) sawfly larvae. Toxicon 2001;39(12):1933-1936. View abstract.

Quimby, P. C., Jr., DeLoach, C. J., Wineriter, S. A., Goolsby, J. A., Sobhian, R., Boyette, C. D., and Abbas, H. K. Biological control of weeds: research by the United States Department of Agriculture-Agricultural Research Service: selected case studies. Pest.Manag.Sci 2003;59(6-7):671-680. View abstract.

Stablein, J. J., Bucholtz, G. A., and Lockey, R. F. Melaleuca tree and respiratory disease. Ann.Allergy Asthma Immunol. 2002;89(5):523-530. View abstract.

Stanaland, B. E., Gennaro, R. N., Bausher, M. G., Klotz, S. D., White, R. S., and Sweeney, M. J. Allergenic cross-reactivity between Callistemon citrinis and Melaleuca quinquenervia pollens. Int Arch Allergy Appl Immunol 1988;86(1):35-41. View abstract.

Stanaland, B. E., Gennaro, R. N., Klotz, S. D., Sweeney, M. J., and White, R. S. Isolation and characterization of cross-reactive allergenic components in Callistemon citrinis and Melaleuca quinquenervia pollen by trans-blot enzyme-linked crossed immunoelectrophoresis. Int Arch Allergy Appl Immunol 1986;80(3):278-284. View abstract.

Subehan, Usia, T., Iwata, H., Kadota, S., and Tezuka, Y. Mechanism-based inhibition of CYP3A4 and CYP2D6 by Indonesian medicinal plants. J Ethnopharmacol. 5-24-2006;105(3):449-455. View abstract.

Sweeney, M., Hosseiny, S., Hunter, S., Klotz, S. D., Gennaro, R. N., and White, R. S. Immunodetection and comparison of melaleuca, bottlebrush, and bahia pollens. Int Arch Allergy Immunol 1994;105(3):289-296. View abstract.

Tsuruga, T., Chun, Y. T., Ebizuka, Y., and Sankawa, U. Biologically active constituents of Melaleuca leucadendron: inhibitors of induced histamine release from rat mast cells. Chem Pharm Bull.(Tokyo) 1991;39(12):3276-3278. View abstract.

Wheeler, G. S., Massey, L. M., and Southwell, I. A. Dietary influences on terpenoids sequestered by the biological control agent Oxyops vitiosa: effect of plant volatiles from different Melaleuca quinquenervia chemotypes and laboratory host species. J Chem Ecol 2003;29(1):189-208. View abstract.

Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182

Franklyn AJ, Bettenridge J, Daykin J, et al. Long-term thyroxine treatment and bone mineral density. Lancet 1992;340:9-13. View abstract.

Osol and Farar. The Dispensatory of the United States of America. 25th ed. JB Lippincott Co., 1955.

CONTINUE SCROLLING FOR RELATED SLIDESHOW

Health Solutions From Our Sponsors