Campral vs. Topamax

Are Campral and Topamax the Same Thing?

Campral (acamprosate calcium) and Topamax (topiramate) are used to help alcohol-dependent patients keep from drinking alcohol.

Campral is used as part of a complete treatment program that includes both counseling and psychological support. Campral is unlikely to be helpful to a person who has not already quit drinking or undergone detoxification. Campral may not be helpful to a person who is also addicted to other substances besides alcohol.

Topamax is used off-label to treat alcoholism. It is primarily used to prevent epileptic seizures and migraine headaches.

Campral and Topamax belong to different drug classes. Campral is a detoxification agent and Topamax is an anticonvulsant.

Side effects of Campral and Topamax that are similar include diarrhea, loss of appetite, drowsiness, dizziness, vision problems or changes in vision, problems with memory or thinking, fatigue/tiredness, weight changes, cold or flu-like symptoms, and changes in taste/unpleasant taste.

Side effects of Campral that are different from Topamax include nausea, vomiting, gas, stomach pain, headache, constipation, back pain, muscle or joint pain, weakness, dry mouth, sleep problems (insomnia), sweating, skin rash, numbness or tingly feeling, impotence, change in or loss of sexual desire, or decreased sexual ability.

Side effects of Topamax that are different from Campral include nervousness, numbness or tingly feeling in the hands or feet, coordination problems, speech/language problems, sensory distortion, confusion, and trouble concentrating or paying attention.

Campral may interact with other drugs.

Topamax may also interact with alcohol, other drugs that make you drowsy (narcotics, sleeping pills, muscle relaxers, or medicines for anxiety or depression), birth control pills, divalproex, or valproic acid.

What Are Possible Side Effects of Campral?

Common side effects of Campral include:

  • diarrhea,
  • nausea,
  • vomiting,
  • gas,
  • stomach pain,
  • loss of appetite,
  • headache,
  • drowsiness,
  • dizziness,
  • vision problems,
  • problems with memory or thinking,
  • constipation,
  • fatigue,
  • weight gain/loss,
  • back pain,
  • muscle or joint pain,
  • weakness,
  • cold or flu-like symptoms,
  • dry mouth,
  • decreased or distorted sense of taste,
  • sleep problems (insomnia),
  • sweating,
  • skin rash,
  • numbness or tingly feeling,
  • impotence,
  • change in or loss of sexual desire, or
  • decreased sexual ability.

Suicidal thoughts may occur during treatment with Campral. Tell your doctor if you feel depressed or have any suicidal thoughts or actions while using Campral. Tell your doctor if you have unlikely but serious side effects of Campral including:

  • mental/mood changes (including severe depression, thoughts of suicide),
  • fainting,
  • fast or pounding heartbeat,
  • vision or hearing changes, or
  • increased thirst.

What Are Possible Side Effects of Topamax?

Common side effects of Topamax include:

  • drowsiness,
  • dry mouth,
  • dizziness,
  • blurred vision,
  • constipation,
  • weight gain,
  • trouble urinating,
  • headache,
  • increased hunger, and
  • changes in taste.

What Is Campral?

Campral (acamprosate calcium) works by restoring the natural balance of chemicals in the brain (neurotransmitters) and is used to help alcohol-dependent patients keep from drinking alcohol. Campral should be used as part of a complete treatment program that includes both counseling and psychological support. Campral is unlikely to be helpful to a person who has not already quit drinking or undergone detoxification. Campral may not be helpful to a person who is also addicted to other substances besides alcohol.

What Is Topamax?

Topamax (topiramate) is an anticonvulsant prescribed for preventing epileptic seizures and migraine headaches. Topamax is available as a generic drug.

SLIDESHOW

Prescription Drug Abuse: Addiction, Health Risks, and Treatments See Slideshow

What Drugs Interact With Campral?

There may be other drugs that can interact with Campral. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Campral should be used only when prescribed during pregnancy. Drinking large amounts of alcohol during pregnancy can cause long-lasting problems (often called fetal alcohol syndrome) in your baby, such as birth defects, growth retardation, and learning disabilities. It is not known whether this drug passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Topamax?

Topamax may interact with narcotic drugs or alcohol, or prescription or over-the-counter medicines to treat a cold, cough, diarrhea, or pain. Tell your doctor all medications and supplements you use.

How Should Campral Be Taken?

The recommended dose of Campral is two 333 mg tablets (each dose should total 666 mg) taken three times daily.

How Should Topamax Be Taken?

Topamax usual adult dose is 200mg twice a day. Drug interactions include acetazolamide (Diamox), methazolamide (Neptazane), dichlorphenamide (Daranide), carbamazepine (Tegretol) and phenytoin (Dilantin) and oral contraceptives. There are no adequate studies of Topamax in pregnant women and it is not known if Topamax is secreted in human breast milk. Use during pregnancy is not recommended unless the potential benefit outweighs the potential unknown risk to the fetus. Topamax passes into breast milk and may harm a nursing baby. Consult your doctor before breastfeeding.

Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References

FDA. Campral Prescribing Information.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021431s013lbl.pdf
Janssen Pharmaceuticals, Inc. Topamax Prescribing Information.
https://www.topamax.com/

Health Solutions From Our Sponsors