Slideshows Images Quizzes
font size

Carotid Artery Disease

Medical Author:
Medical Editor:

What is carotid artery disease?

The carotid arteries provide blood supply to the head. There are two common carotid arteries, located on each side of the neck, that divide into the internal and external carotid arteries. The external carotid artery provides blood supply to the scalp, face, and neck while the internal carotid artery supplies blood to the brain.

Narrowing of the internal carotid artery may decrease blood supply to half of the brain that it supplies. This narrowing called atherosclerosis (atheroma = lump of plaque + sclerosis = hardening) occurs because of the accumulation of plaque on the inside of the artery wall. Plaque begins as a soft, waxy collection of cholesterol and triglycerides but over time begins to harden and calcify. Often it occurs where increased blood pressure and blood turbulence irritates the inner lining of the artery and this often occurs where the internal and external carotid arteries split (bifurcation).

As the carotid artery begins to further narrow, the pressure within the artery continues to increase. This may cause the plaque to rupture, causing blood clots to form. A large clot may completely block (occlude) the artery or smaller clots and bits of plaque may travel into smaller arteries within the brain and cause disruption of blood supply to parts of brain tissue.

It is only when a stroke or transient ischemic attack occurs, or a bruit (blowing or whistling sound) is found on physical examination by your doctor, that the diagnosis of carotid artery disease is usually made. Otherwise, the narrowing carotid artery does not cause symptoms.

What are the causes of carotid artery disease?

Carotid artery disease occurs because of damage to the inner lining of the artery. This is a gradual process that is associated with smoking, high blood pressure, high cholesterol levels, and poorly controlled diabetes. These all may cause minor damage to the inner walls of an artery, and during the healing process, inflammation may occur and plaque may begin to form.

Over time, the area of plaque may grow and narrow the lumen of the artery, the channel where blood flows. It becomes a vicious circle as the narrower lumen increases pressure within the artery and blood turbulence, which leads to more arterial wall damage and more plaque formation.

Picture of Carotid Artery Disease
Picture of Carotid Artery Disease

Medically Reviewed by a Doctor on 11/5/2015


Cholesterol Management

Tips to keep it under control.

Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations

Health Solutions From Our Sponsors