Casporyn Side Effects Center

Last updated on RxList: 12/7/2021
Casporyn Side Effects Center

What Is Casporyn HC?

Casporyn HC (neomycin and polymyxin B sulfates and hydrocortisone otic suspension) is an antibacterial and anti-inflammatory suspension used for the treatment of superficial bacterial infections of the external auditory (ear) canal caused by organisms susceptible to the action of the antibiotics, and for the treatment of infections of mastoidectomy and fenestration cavities caused by organisms susceptible to the antibiotics.

What Are Side Effects of Casporyn HC?

Common side effects of Casporyn HC include:

Dosage for Casporyn HC

The adult dose of Casporyn HC is 4 drops of the suspension instilled into the affected ear 3 or 4 times daily. For children, 3 drops are suggested because of the smaller capacity of the ear canal.

What Drugs, Substances, or Supplements Interact with Casporyn HC?

Casporyn HC may interact with other drugs. Tell your doctor all medications and supplements you use.

Casporyn HC During Pregnancy or Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Casporyn HC; it is unknown how it would affect a fetus. Hydrocortisone appears in breast milk following oral administration of the drug. Consult your doctor before breastfeeding.

Additional Information

Our Casporyn HC Otic Suspension (neomycin and polymyxin B sulfates and hydrocortisone otic suspension) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Casporyn Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • numbness or tingly feeling under your skin;
  • hearing problems (even long after you stop taking neomycin);
  • muscle twitching, seizure;
  • weak or shallow breathing; or
  • kidney problems--swelling, urinating less, feeling tired or short of breath.

Common side effects may include:

  • nausea, vomiting; or
  • diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Casporyn (Neomycin Optic Suspension)


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Casporyn Professional Information


Neomycin occasionally causes skin sensitization. Ototoxicity and nephrotoxicity have also been reported (see WARNINGS). Adverse reactions have occurred with topical use of antibiotic combinations including neomycin and polymyxin B. Exact incidence figures are not available since no denominator of treated patients is available. The reaction occurring most often is allergic sensitization.

The following local adverse reactions have been reported with topical corticosteroids, especially under occlusive dressings: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae and miliaria. Stinging and burning have been reported rarely when this drug has gained access to the middle ear.

To report SUSPECTED ADVERSE REACTIONS, contact Casper Pharma LLC. at 1-844-5-CASPER (1- 844-522-7737) or FDA at 1-800-FDA-1088 or


No Information Provided

Read the entire FDA prescribing information for Casporyn (Neomycin Optic Suspension)

© Casporyn Patient Information is supplied by Cerner Multum, Inc. and Casporyn Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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