Catapres vs. Minipress

Are Catapres and Minipress the Same Thing?

Catapres (clonidine hydrochloride) and Minipress (prazosin hydrochloride) are used to treat high blood pressure (hypertension).

Catapres and Minipris belong to different drug classes. Catapres is a centrally acting alpha-agonist and Minipress is an alpha-adrenergic blocker.

What Are Possible Side Effects of Catapres?

Common side effects of Catapres include:

Many side effects of Catapres may go away after several doses. Serious side effects of Catapres include hypotension, bradycardia, congestive heart failure, weakness, and edema.

What Are Possible Side Effects of Minipress?

Common side effects of Minipress include:

Other side effects of Minipress include:

  • lightheadedness or dizziness upon standing, especially after the first dose and shortly after taking a dose of the drug during the first week of treatment.


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What is Catapres?

Catapres (clonidine hydrochloride) is a centrally acting alpha-agonist hypotensive agent used to treat hypertension. Catapres is available as a generic named clonidine (tablets and patches).

What is Minipress?

Minipress (clonidine hydrochloride) extended-release is a centrally acting alpha2-adrenergic agonist used to treat attention deficit hyperactivity disorder (ADHD). Minipress is available in generic form.

What Drugs Interact With Catapres?

Catapres may interact with other drugs that make you sleepy or slow your breathing (sleeping pills, narcotics, muscle relaxers, or medicines for anxiety, depression, or seizures), antidepressants, beta-blockers, digitalis, other products containing clonidine, or other drugs to treat high blood pressure or heart problems.

Catapres may also interact with digoxin or medicines to treat psychiatric disorders.

What Drugs Interact With Minipress?

Minipress may interact with other blood pressure medications.

Minipress may also interact with propranolol.


Salt and sodium are the same. See Answer

How Should Catapres Be Taken?

Catapres (clonidine hydrochloride, USP and TTS) is available in strengths of 0.1, 0.2 and 0.3 mg tablets and patches for transdermal administration (TTS form). No adequate, well-controlled studies have been conducted in pregnant or breastfeeding women; this drug may be used during pregnancy only if clearly needed. Safety and effectiveness in pediatric patients has not been established although some pediatric physicians have used the drug to treat hypertensive children.

How Should Minipress Be Taken?

Initial dose of Minipress is 1 mg two or three times a day. The usual therapeutic dose ranges from 6 mg to 15 mg daily given in divided doses.


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Medical Editor: John P. Cunha, DO, FACOEP

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