Cerubidine

Last updated on RxList: 8/3/2012
Cerubidine Side Effects Center

Last reviewed on RxList 2/5/2016

Cerubidine (daunorubicin) is a cancer (antineoplastic) medication used in the treatment of leukemia (blood cancer). Cerubidine is available in generic form. Common side effects of Cerubidine include nausea, vomiting, constipation, diarrhea, and loss of appetite. Cerubidine may cause urine to turn a reddish color. This is a normal, harmless effect of Cerubidine and should not be mistaken for blood in the urine. Temporary hair loss is a common side effect of Cerubidine. Normal hair growth should return after treatment with Cerubidine has ended.

Dosage of Cerubidine is determined by a physician and the drug is administered in a clinical setting. Cerubidine may interact with cyclophosphamide, methotrexate, or “live” vaccines. Tell your doctor if you have had previous treatment with doxorubicin, doxorubicin liposomal, daunorubicin, daunorubicin liposomal, idarubicin, or mitoxantrone. Because there is a maximum amount of these medications that should be administered to an individual, you may not be able to use Cerubidine. Tell your doctor all medications and supplements you use. Cerubidine is not recommended for use during pregnancy. It may harm a fetus. If you become pregnant or think you may be pregnant, tell your doctor. Males and females using this drug should use birth control (e.g., birth control pills, condoms) during treatment; consult your doctor. It is unknown if this drug passes into breast milk. Because of the possible risk to the infant, breastfeeding while using this drug is not recommended.

Our Cerubidine (daunorubicin) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

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Cerubidine Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • pain, burning, irritation, or skin changes where the injection was given;
  • heart problems--swelling, rapid weight gain, feeling short of breath;
  • low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed;
  • kidney problems--little or no urination, swelling in your feet or ankles, feeling tired; or
  • liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects may include:

  • sores or white patches in or around your mouth, trouble swallowing or talking, dry mouth, bad breath, altered sense of taste;
  • red discoloration of the urine;
  • nausea, vomiting; or
  • hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Cerubidine (Daunorubicin)

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Cerubidine Professional Information

SIDE EFFECTS

Dose-limiting toxicity includes myelosuppression and cardiotoxicity (See WARNINGS). Other reactions include:

Cutaneous: Reversible alopecia occurs in most patients. Rash, contact dermatitis and urticaria have occurred rarely.

Gastrointestinal:Acute nausea and vomiting occur but are usually mild. Antiemetic therapy may be of some help. Mucositis may occur 3 to 7 days after administration. Diarrhea and abdominal pain have occasionally been reported.

Local: If extravasation occurs during administration, severe local tissue necrosis, severe celluli-tis, thrombophlebitis, or painful induration can result.

Acute Reactions: Rarely, anaphylactoid reaction, fever, and chills can occur. Hyperuricemia may occur, especially in patients with leukemia, and serum uric acid levels should be monitored.

Read the entire FDA prescribing information for Cerubidine (Daunorubicin)

© Cerubidine Patient Information is supplied by Cerner Multum, Inc. and Cerubidine Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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