Cholera Vaccine

Medical Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 2/2/2022
Cholera Vaccine Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Cholera Vaccine?

Cholera vaccine is an immunization against cholera indicated only for individuals traveling to or residing in countries where cholera is endemic or epidemic. Cholera vaccine is available in generic form.

What Are Side Effects of Cholera Vaccine?

Common side effects of cholera vaccine include:

  • injection site reactions (skin redness, hardening of the skin, pain, and tenderness) that may last a few days
  • general feeling of being unwell (malaise)
  • headache
  • fever
  • diarrhea
  • nausea
  • vomiting
  • abdominal pain or cramps
  • joint pain
  • rash
  • numbness
  • tingling flu-like symptoms

Dosage for Cholera Vaccine

The primary immunizing course consists of two doses of cholera vaccine administered one week to one month or more apart.

What Drugs, Substances, or Supplements Interact with Cholera Vaccine?

Cholera vaccine may interact with yellow fever vaccines. Tell your doctor all medications and supplements you use and all vaccines you recently received.

Cholera Vaccine During Pregnancy or Breastfeeding

During pregnancy, cholera vaccine should be given only if prescribed. Consult your doctor before breastfeeding.

Additional Information

Our Cholera Vaccine Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Cholera Vaccine Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common side effects may include:

  • nausea, vomiting, diarrhea;
  • stomach pain, loss of appetite;
  • headache; or
  • feeling tired.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report vaccine side effects to the US Department of Health and Human Services at 1-800-822-7967.

Read the entire detailed patient monograph for Cholera Vaccine (Cholera Vaccine)


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Cholera Vaccine Professional Information


Local reactions manifested by erythema, induration, pain, and tenderness at the site of injection occur in most recipients, and such local reactions may persist for a few days.

Recipients frequently develop malaise, headache, and mild-to-moderate temperature elevations which may persist for 1 to 2 days. 1,4

Read the entire FDA prescribing information for Cholera Vaccine (Cholera Vaccine)

© Cholera Vaccine Patient Information is supplied by Cerner Multum, Inc. and Cholera Vaccine Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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