Cleocin vs. Bactrim

Are Cleocin and Bactrim the Same Thing?

Cleocin (clindamycin hydrochloride) and Bactrim (sulfamethoxazole and trimethoprim) are antibiotics used to treat serious infections caused by bacteria.

Cleocin and Bactrim belong to different drug classes. Cleocin is a lincomycin antibiotic and Bactrim is a combination of a sulfonamide antibiotic (a "sulfa" drug) and a folic acid inhibitor.

What Are Possible Side Effects of Cleocin?

Common side effects of Cleocin include:

  • burning,
  • itching,
  • dryness,
  • redness,
  • oily skin,
  • skin peeling, or
  • other irritation of treated skin.

Tell your doctor if you have serious side effects of Cleocin including:

  • severe redness, itching, or dryness of treat skin areas; or
  • diarrhea that is watery or bloody.

What Are Possible Side Effects of Bactrim?

Common side effects of Bactrim include:

Tell your doctor if you experience serious side effects of Bactrim including:

What is Cleocin?

Cleocin (clindamycin) is an antibiotic used to treat severe acne. Cleocin T is available in generic form.

What is Bactrim?

Bactrim (sulfamethoxazole and trimethoprim) DS is a combination of two antibiotics used to treat urinary tract infections, acute otitis media, bronchitis, Shigellosis, Pneumocystis pneumonia, traveler's diarrhea, methicillin-resistant Staphylococcus aureus (MRSA), and other bacterial infections susceptible to this antibiotic. Bactrim is available as a generic drug.

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What Drugs Interact With Cleocin?

Cleocin may interact with other neuromuscular blocking agents or erythromycin.

What Drugs Interact With Bactrim?

Bactrim may interact with antidepressants, blood thinners, cyclosporine, oral diabetes medications, digoxin, diuretics (water pills), indomethacin, leucovorin, calcium folinate, methotrexate, heart or blood pressure medications, or seizure medications

How Should Cleocin Be Taken?

Apply a thin film of Cleocin T Topical twice daily to affected area. Cleocin T may interact with erythromycin topical or erythromycin taken by mouth. Tell your doctor all medications you are taking. The dose of Cleocin HCl for adults is 150 to 300 mg every 6 hours. For more severe infections is 300 to 450 mg every 6 hours. The dose of for pediatric patients is 8 to 16 mg/kg/day divided in three or four equal doses. For more severe infections, 16 to 20 mg/kg/day divided in three or four equal doses.

How Should Bactrim Be Taken?

Bactrim is available in tablets in two strengths; 400 mg sulfamethoxazole and 80 mg trimethoprim and the "DS" form which means double strength, 800 mg sulfamethoxazole and 160 mg trimethoprim. Patients should follow their doctor's instructions and take all of the Bactrim prescribed.

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References
Medical Editor: John P. Cunha, DO, FACOEP

SOURCE:

RxList. Cleocin Medication Guide.

https://www.rxlist.com/cleocin-drug.htm#medguide

RxList. Clindamycin Medication Guide.

https://www.rxlist.com/clindamycin-drug.htm

https://www.rxlist.com/bactrim-drug.htm#medguide

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