Medical Editor: John P. Cunha, DO, FACOEP
Clindamycin phosphate topical solution is a topical (for the skin) antibiotic used to treat acne vulgaris. Clindamycin phosphate topical solution is available in generic form. Common side effects of clindamycin phosphate topical solution include:
- skin burning or itching,
- dry skin,
- skin redness,
- oily skin,
- skin peeling,
- stomach upset, or
- abdominal pain.
Apply a thin film of Clindamycin Phosphate Topical Solution or use a Clindamycin Phosphate Topical Solution pledget (pad) twice daily to affected area. More than one pledget may be used if needed. Discard any used pledgets and wash hands thoroughly after application. Clindamycin Phosphate Topical Solution may interact with other neuromuscular blocking agents. There may be other drugs that can interact with Clindamycin Phosphate Topical Solution. Tell your doctor all prescription and over-the-counter medications you are taking. Clindamycin Phosphate Topical Solution should be used during pregnancy only if prescribed. It is not known if the topical form of this medication passes in breast milk. Oral forms of clindamycin pass into breast milk. Consult your doctor before breastfeeding.
Our Clindamycin Phosphate Topical Solution Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In 18 clinical studies of various formulations of clindamycin phosphate using placebo vehicle and/or active comparator drugs as controls, patients experienced a number of treatment emergent adverse dermatologic events [see table].
Number of Patients Reporting Events
|Treatment Emergent Adverse Event||Solution
|Burning||62 (11)||15 (10)||17 (11)|
|Itching||36 (7)||15 (10)||17 (11)|
|Burning/Itching||60 (11)||# (-)||# (-)|
|Dryness||105(19)||34 (23)||29 (18)|
|Erythema||86 (16)||10 (7)||22 (14)|
|Oiliness/OiSy Skin||8 (1)||26 (18)||12* (10)|
|Peeling||61 (11)||# (-)||11 (7)|
Orally and parenterally administered clindamycin has been associated with severe colitis which may end fatally.
Cases of diarrhea, bloody diarrhea and colitis (including pseudomembranous colitis) have been reported as adverse reactions in patients treated with oral and parenteral formulations of clindamycin and rarely with topical clindamycin (see WARNINGS).
To report SUSPECTED ADVERSE REACTIONS, contact G&W Laboratories , Inc. at 1-800- 922-1038 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Read the entire FDA prescribing information for Clindamycin Phosphate Topical Solution (Clindamycin Phosphate Topical Solution)