Clindamycin Phosphate Topical Solution

Last updated on RxList: 3/1/2021
Clindamycin Phosphate Topical Solution Side Effects Center

What Is Clindamycin Phosphate?

Clindamycin phosphate topical solution is a topical (for the skin) antibiotic used to treat acne vulgaris. Clindamycin phosphate topical solution is available in generic form.

What Are Side Effects of Clindamycin Phosphate?

Common side effects of clindamycin phosphate topical solution include:

  • skin burning or itching,
  • dry skin,
  • skin redness,
  • oily skin,
  • skin peeling,
  • stomach upset, or
  • abdominal pain.

Dosage for Clindamycin Phosphate

Apply a thin film of Clindamycin Phosphate Topical Solution or use a Clindamycin Phosphate Topical Solution pledget (pad) twice daily to affected area. More than one pledget may be used if needed. Discard any used pledgets and wash hands thoroughly after application.

What Drugs, Substances, or Supplements Interact with Clindamycin Phosphate?

Clindamycin Phosphate Topical Solution may interact with other neuromuscular blocking agents. There may be other drugs that can interact with Clindamycin Phosphate Topical Solution. Tell your doctor all prescription and over-the-counter medications you are taking.

Clindamycin Phosphate During Pregnancy and Breastfeeding

Clindamycin Phosphate Topical Solution should be used during pregnancy only if prescribed. It is not known if the topical form of this medication passes in breast milk. Oral forms of clindamycin pass into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Clindamycin Phosphate Topical Solution Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

Acne is the result of an allergy. See Answer
Clindamycin Phosphate Topical Solution Consumer Information

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Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.

Call your doctor at once if you have:

  • any change in bowel habits;
  • severe stomach pain, diarrhea that is watery or bloody;
  • little or no urination; or
  • a metallic taste in your mouth (after clindamycin injection).

Common side effects may include:

  • nausea, vomiting, stomach pain;
  • mild skin rash; or
  • vaginal itching or discharge;

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Clindamycin Phosphate Topical Solution (Clindamycin Phosphate Topical Solution)

SLIDESHOW

Skin Health: 15 Tips for Clear Skin See Slideshow
Clindamycin Phosphate Topical Solution Professional Information

SIDE EFFECTS

In 18 clinical studies of various formulations of clindamycin phosphate using placebo vehicle and/or active comparator drugs as controls, patients experienced a number of treatment emergent adverse dermatologic events [see table].

Number of Patients Reporting Events

Treatment Emergent Adverse Event Solution
n=553 [%)
Gel
n=148(%)
Lotion
n=160(%)
Burning 62 (11) 15 (10) 17 (11)
Itching 36 (7) 15 (10) 17 (11)
Burning/Itching 60 (11) # (-) # (-)
Dryness 105(19) 34 (23) 29 (18)
Erythema 86 (16) 10 (7) 22 (14)
Oiliness/OiSy Skin 8 (1) 26 (18) 12* (10)
Peeling 61 (11) # (-) 11 (7)

Orally and parenterally administered clindamycin has been associated with severe colitis which may end fatally.

Cases of diarrhea, bloody diarrhea and colitis (including pseudomembranous colitis) have been reported as adverse reactions in patients treated with oral and parenteral formulations of clindamycin and rarely with topical clindamycin (see WARNINGS).

Abdominal pain, gastrointestinal disturbances, gram-negative folliculitis, eye pain and contact dermatitis have also been reported in association with the use of topical formulations of clindamycin.

To report SUSPECTED ADVERSE REACTIONS, contact G&W Laboratories , Inc. at 1-800- 922-1038 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Read the entire FDA prescribing information for Clindamycin Phosphate Topical Solution (Clindamycin Phosphate Topical Solution)

© Clindamycin Phosphate Topical Solution Patient Information is supplied by Cerner Multum, Inc. and Clindamycin Phosphate Topical Solution Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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