clindamycin

Medical Reviewer: John P. Cunha, DO, FACOEP Last updated on RxList: 8/11/2021
clindamycin Side Effects Center

What Is Clindam (clindamycin)?

Clindam (clindamycin) is an antibiotic used to treat serious infections caused by bacteria. Clindamycin is available in generic form.

Clindam (clindamycin) is an antibiotic, lincosamide drug class.

What Are Side Effects of Clindam (clindamycin)?

Common side effects of Clindam (clindamycin) include

Other side effects of Clindam (clindamycin) include

Tell your doctor if you experience serious side effects of Clindamycin including:

Dosage for Clindam (clindamycin)

The dose of Clindamycin for adults is 150 to 300 mg every 6 hours. For more severe infections is 300 to 450 mg every 6 hours.

Clindam (clindamycin) In Children

The dose for pediatric patients is 8 to 16 mg/kg/day divided in three or four equal doses. For more severe infections, 16 to 20 mg/kg/day divided in three or four equal doses.

What Drugs, Substances, or Supplements Interact with Clindamycin?

Other drugs may interact with Clindamycin HCl. Tell your doctor all prescription and over-the-counter medications and supplements you use.

Clindamycin During Pregnancy and Breastfeeding

During pregnancy, Clindamycin should be used only when prescribed. This medication passes into breast milk. Though there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.

Additional Information

Our Clindamycin Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

Bowel regularity means a bowel movement every day. See Answer
clindamycin Consumer Information

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Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.

Call your doctor at once if you have:

  • any change in bowel habits;
  • severe stomach pain, diarrhea that is watery or bloody;
  • little or no urination; or
  • a metallic taste in your mouth (after clindamycin injection).

Common side effects may include:

  • nausea, vomiting, stomach pain;
  • mild skin rash; or
  • vaginal itching or discharge;

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for clindamycin (Clindamycin)

SLIDESHOW

Fungal Skin Infections: Types, Symptoms, and Treatments See Slideshow
clindamycin Professional Information

SIDE EFFECTS

The following reactions have been reported with the use of clindamycin.

Infections and Infestations: Clostridium difficile colitis

Gastrointestinal: Abdominal pain, pseudomembranous colitis, esophagitis, nausea, vomiting, and diarrhea (see BOXED WARNING). The onset of pseudomembranous colitis symptoms may occur during or after antibacterial treatment (see WARNINGS). Esophageal ulcer has been reported. An unpleasant or metallic taste has been reported after oral administration.

Hypersensitivity Reactions: Generalized mild to moderate morbilliform-like (maculopapular) skin rashes are the most frequently reported adverse reactions. Vesiculobullous rashes, as well as urticaria, have been observed during drug therapy. Severe skin reactions such as Toxic Epidermal Necrolysis, some with fatal outcome, have been reported (See WARNINGS). Cases of Acute Generalized Exanthematous Pustulosis (AGEP), erythema multiforme, some resembling Stevens-Johnson syndrome, anaphylactic shock, anaphylactic reaction and hypersensitivity have also been reported.

Skin and Mucous Membranes: Pruritus, vaginitis, angioedema and rare instances of exfoliative dermatitis have been reported. (See Hypersensitivity Reactions.)

Liver: Jaundice and abnormalities in liver function tests have been observed during clindamycin therapy.

Renal: Although no direct relationship of clindamycin to renal damage has been established, renal dysfunction as evidenced by azotemia, oliguria, and/or proteinuria has been observed.

Hematopoietic: Transient neutropenia (leukopenia) and eosinophilia have been reported. Reports of agranulocytosis and thrombocytopenia have been made. No direct etiologic relationship to concurrent clindamycin therapy could be made in any of the foregoing.

Immune System: Drug reaction with eosinophilia and systemic symptoms (DRESS) cases have been reported.

Musculoskeletal: Cases of polyarthritis have been reported.

Read the entire FDA prescribing information for clindamycin (Clindamycin)

© clindamycin Patient Information is supplied by Cerner Multum, Inc. and clindamycin Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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