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Clinoril vs. Aspirin

  • Medical and Pharmacy Editor: John P. Cunha, DO, FACOEP
    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, is a U.S. board-certified Emergency Medicine Physician. Dr. Cunha's educational background includes a BS in Biology from Rutgers, the State University of New Jersey, and a DO from the Kansas City University of Medicine and Biosciences in Kansas City, MO. He completed residency training in Emergency Medicine at Newark Beth Israel Medical Center in Newark, New Jersey.

Are Clinoril and Aspirin the Same Thing?

Clinoril (sulindac) and aspirin are nonsteroidal anti-inflammatory drugs (NSAIDs) used to treat pain or inflammation caused by arthritis, ankylosing spondylitis, tendinitis, bursitis, or gout.

Aspirin is also used to prevent blood clots, to reduce the risk of strokes and heart attacks.

Aspirin is available over-the-counter (OTC) and as a generic.

Side effects of Clinoril and aspirin that are similar include upset stomach, stomach or abdominal pain, heartburn, nausea, or headache.

Side effects of Clinoril that are different from aspirin include vomiting, gas, bloating, diarrhea, constipation, dizziness, fatigue, nervousness, skin itching or rash, dry mouth, increased sweating, runny nose, blurred vision, or ringing in your ears.

Side effects of aspirin that are different from Clinoril include rash, gastrointestinal ulcerations, drowsiness, cramping, gastritis, and bleeding.

Both Clinoril and aspirin may interact with alcohol, antidepressants, blood thinners, other nonsteroidal anti-inflammatory drugs (NSAIDs), or other cold/allergy/pain medicine that contains NSAIDs.

Clinoril may also interact with cyclosporine, diuretics (water pills), lithium, methotrexate, steroids, heart or blood pressure medications, oral diabetes medications, ACE inhibitors, or aspirin.

Aspirin may also interact with other salicylates such as Nuprin Backache Caplet, Kaopectate, KneeRelief, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate.

What Are Possible Side Effects of Clinoril?

Common side effects of Clinoril include:

  • upset stomach,
  • stomach pain,
  • heartburn,
  • nausea,
  • vomiting,
  • gas,
  • bloating,
  • diarrhea,
  • constipation,
  • dizziness,
  • fatigue,
  • headache,
  • nervousness,
  • skin itching or rash,
  • dry mouth,
  • increased sweating,
  • runny nose,
  • blurred vision, or
  • ringing in your ears.

Tell your doctor if you have unlikely but serious side effects of Clinoril including:

  • swelling of the hands or feet (edema),
  • sudden or unexplained weight gain,
  • mental/mood changes,
  • difficult or painful swallowing, or
  • unusual tiredness.

What Are Possible Side Effects of Aspirin?

Common side effects of Aspirin include:

  • rash,
  • gastrointestinal ulcerations,
  • abdominal pain,
  • upset stomach,
  • heartburn,
  • drowsiness,
  • headache,
  • cramping,
  • nausea,
  • gastritis, and
  • bleeding

What Is Clinoril?

Clinoril (Sulindac) is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain or inflammation caused by arthritis, ankylosing spondylitis, tendinitis, bursitis, or gout. Clinoril is available in generic form.

What Is Aspirin?

Aspirin (aspirin) is a nonsteroidal anti-inflammatory drug (NSAID) prescribed for treating fever, pain, inflammation in the body, prevention of blood clots, and reduction of the risk of strokes and heart attacks.

What Drugs Interact With Clinoril?

Clinoril may interact with cyclosporine, diuretics (water pills), lithium, methotrexate, blood thinners, steroids, heart or blood pressure medications, oral diabetes medications, ACE inhibitors, aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs). Tell your doctor all medications you are taking. Clinoril should be used only when prescribed during the first 6 months of pregnancy. It is not recommended for use during the last 3 months of pregnancy due to possible harm to a fetus and interference with normal labor/delivery. It is unknown if this drug passes into breast milk. Breastfeeding while using this medication is not recommended.

What Drugs Interact With Aspirin?

Aspirin may interact with alcohol, antidepressants, blood thinners, other nonsteroidal anti-inflammatory drugs (NSAIDs), or other cold/allergy/pain medicine that contains NSAIDs.

Aspirin may also interact with other salicylates such as Nuprin Backache Caplet, Kaopectate, KneeRelief, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate.

How Should Clinoril Be Taken?

Clinoril is administered under a physician's supervision. The dose of Clinoril varies depending on the disorder being treated and the number of infusions (doses) needed.

How Should Aspirin Be Taken?

Bayer Aspirin dose ranges from 50 mg to 6000 mg daily.

Reviewed on 4/11/2019

SOURCE:

FDA. Clinoril Product Information.

https://www.fda.gov/downloads/Drugs/DrugSafety/ucm088573.pdf

Bayer. Aspirin Product Information.

https://www.bayeraspirin.com/

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