Clinoril vs. Celebrex

Are Clinoril and Celebrex the Same Thing?

Clinoril (sulindac) and Celebrex (celecoxib) are nonsteroidal anti-inflammatory drugs (NSAIDs) used to treat pain or inflammation caused by arthritis,

Clinoril is also used to treat pain or inflammation caused by ankylosing spondylitis, tendinitis, bursitis, or gout.

Celebrex is also used to treat familial FAP, acute pain, and menstrual cramps.

Side effects of Clinoril and Celebrex that are similar include upset stomach, stomach/abdominal pain, heartburn/indigestion, nausea, gas, bloating, diarrhea, dizziness, headache, nervousness, skin rash, or runny nose.

Side effects of Clinoril that are different from Celebrex include vomiting, constipation, fatigue, itching, dry mouth, increased sweating, blurred vision, or ringing in your ears.

Side effects of Celebrex that are different from Clinoril include stuffy nose, sore throat, and insomnia.

Both Clinoril and Celebrex may interact with alcohol, aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs), other cold/allergy/pain medicine that contains NSAIDs, diuretics (water pills), lithium, blood thinners, ACE inhibitors, antidepressants, or heart or blood pressure medications.

Clinoril may also interact with cyclosporine, methotrexate, steroids, or oral diabetes medications.

Celebrex may also interact with fluconazole.

What Are Possible Side Effects of Clinoril?

Common side effects of Clinoril include:

  • upset stomach,
  • stomach pain,
  • heartburn,
  • nausea,
  • vomiting,
  • gas,
  • bloating,
  • diarrhea,
  • constipation,
  • dizziness,
  • fatigue,
  • headache,
  • nervousness,
  • skin itching or rash,
  • dry mouth,
  • increased sweating,
  • runny nose,
  • blurred vision, or
  • ringing in your ears.

Tell your doctor if you have unlikely but serious side effects of Clinoril including:

  • swelling of the hands or feet (edema),
  • sudden or unexplained weight gain,
  • mental/mood changes,
  • difficult or painful swallowing, or
  • unusual tiredness.

What Are Possible Side Effects of Celebrex?

Common side effects of Celebrex include:

  • headache,
  • abdominal pain,
  • indigestion,
  • diarrhea,
  • nausea,
  • upset stomach,
  • bloating,
  • gas,
  • dizziness,
  • nervousness,
  • headache,
  • runny or stuffy nose,
  • sore throat,
  • skin rash, and
  • insomnia.

Celebrex may cause serious stomach and intestinal ulcers.

What Is Clinoril?

Clinoril (Sulindac) is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain or inflammation caused by arthritis, ankylosing spondylitis, tendinitis, bursitis, or gout. Clinoril is available in generic form.

What Is Celebrex?

Celebrex used to treat pain and redness, swelling, and heat (inflammation) from medical conditions such as different types of arthritis, menstrual cramps, and other types of short-term pain.

SLIDESHOW

What Is Rheumatoid Arthritis (RA)? Symptoms, Treatment, Diagnosis See Slideshow

What Drugs Interact With Clinoril?

Clinoril may interact with cyclosporine, diuretics (water pills), lithium, methotrexate, blood thinners, steroids, heart or blood pressure medications, oral diabetes medications, ACE inhibitors, celebrex or other NSAIDs (nonsteroidal anti-inflammatory drugs). Tell your doctor all medications you are taking. Clinoril should be used only when prescribed during the first 6 months of pregnancy. It is not recommended for use during the last 3 months of pregnancy due to possible harm to a fetus and interference with normal labor/delivery. It is unknown if this drug passes into breast milk. Breastfeeding while using this medication is not recommended.

What Drugs Interact With Celebrex?

Do not take Celebrex:

How Should Clinoril Be Taken?

Clinoril is administered under a physician's supervision. The dose of Clinoril varies depending on the disorder being treated and the number of infusions (doses) needed.

How Should Celebrex Be Taken?

Carefully consider the potential benefits and risks of Celebrex and other treatment options before deciding to use Celebrex. Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals.

QUESTION

The term arthritis refers to stiffness in the joints. See Answer
Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
SOURCE:

FDA. Clinoril Product Information.

https://www.fda.gov/downloads/Drugs/DrugSafety/ucm088573.pdf

Pfizer. Celebrex Product Information.

https://www.celebrex.com/

Health Solutions From Our Sponsors