Medical Editor: John P. Cunha, DO, FACOEP
Clobex (clobetasol propionate) Lotion is a topical (for the skin) steroid used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis. Clobex Lotion is available in generic form. Common side effects of Clobex Lotion include:
- mild skin rash,
- burning, or
- dry or cracking skin,
- thinning or softening of the skin,
- skin rash or irritation around the mouth,
- swollen hair follicles,
- spider veins,
- changes in color of treated skin,
- crusting of treated skin, or
- stretch marks.
Tell your doctor if you have severe irritation of any treated skin, or if you show signs of absorbing Clobex Lotion topical through your skin, such as:
- blurred vision, or
- seeing halos around lights,
- mood changes,
- sleep problems (insomnia),
- weight gain,
- puffiness in your face,
- muscle weakness, or
- feeling tired.
The recommended dose is to apply Clobex Lotion 0.05% to the affected skin areas twice daily and rub in gently and completely. It is not likely other drugs you take orally or inject will have an effect on topically applied Clobex. But many drugs can interact with each other. Tell your doctor all medications and supplements you use. During pregnancy, Clobex should be used only if prescribed. It may be harmful to a fetus. It is unknown if this medication passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.
Our Clobex (clobetasol propionate) Lotion Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Although the risk of serious side effects is low when clobetasol topical is applied to the skin, you should be aware of side effects that can occur if the medication is absorbed into your bloodstream.
Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing clobetasol topical through your skin, such as:
- blurred vision, or seeing halos around lights;
- mood changes;
- sleep problems (insomnia);
- weight gain, puffiness in your face; or
- muscle weakness, feeling tired.
Less serious side effects may include:
- mild skin rash, itching, burning, or redness;
- dry or cracking skin;
- thinning or softening of your skin;
- skin rash or irritation around your mouth;
- swollen hair follicles;
- temporary hair loss;
- spider veins;
- changes in color of treated skin;
- blisters, pimples, or crusting of treated skin; or
- stretch marks.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Clobex Lotion (Clobetasol Propionate Lotion)
In controlled clinical trials with CLOBEX® (clobetasol propionate) Lotion, 0.05%, the following adverse reactions have been reported: burning/stinging, skin dryness, irritation, erythema, folliculitis, pruritus, skin atrophy, and telangiectasia.
Other local adverse events occurred at rates less than 1.0%. Similar rates of local adverse reactions were reported in the comparator (clobetasol propionate cream, 0.05%). Most local adverse events were rated as mild to moderate and they are not affected by age, race or gender.
The following additional local adverse reactions have been reported with topical corticosteroids. They may occur more frequently with the use of occlusive dressings and higher potency corticosteroids, including clobetasol propionate. These reactions are listed in an approximate decreasing order of occurrence: irritation, dryness, folliculitis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, striae and miliaria.
Read the entire FDA prescribing information for Clobex Lotion (Clobetasol Propionate Lotion)
© Clobex Lotion Patient Information is supplied by Cerner Multum, Inc. and Clobex Lotion Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.