Clobex Shampoo

Last updated on RxList: 5/3/2021
Clobex Shampoo Side Effects Center

What Is Clobex Shampoo?

Clobex (clobetasol propionate) Shampoo is a topical (for the skin) steroid used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis. Clobex Shampoo is available in generic form.

What Are Side Effects of Clobex Shampoo?

Common side effects of Clobex Shampoo include:

  • mild skin rash,
  • itching,
  • burning, or redness,
  • dry or cracking skin,
  • thinning or softening of the skin,
  • skin rash or irritation around the mouth,
  • swollen hair follicles,
  • temporary hair loss,
  • spider veins,
  • changes in color of treated skin,
  • blisters,
  • pimples,
  • crusting of treated skin, or
  • stretch marks

Dosage for Clobex Shampoo

The recommended dose of Clobex Shampoo is to apply onto dry (not wet) scalp once a day in a thin film to the affected areas only, and left in place for 15 minutes before lathering and rinsing.

What Drugs, Substances, or Supplements Interact with Clobex Shampoo?

It is not likely other drugs you take orally or inject will have an effect on topically applied Clobex. But many drugs can interact with each other. Tell your doctor all medications and supplements you use.

Clobex Shampoo During Pregnancy or Breastfeeding

During pregnancy, Clobex should be used only if prescribed. It may be harmful to a fetus. It is unknown if this medication passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

Additional Information

Our Clobex (clobetasol propionate) Shampoo Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

Psoriasis causes the top layer of skin cells to become inflamed and grow too quickly and flake off. See Answer
Clobex Shampoo Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • worsening of your skin condition;
  • redness, warmth, swelling, oozing, or severe irritation of any treated skin;
  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or
  • possible signs of absorbing this medicine through your skin--weight gain in your face and shoulders, slow wound healing, skin discoloration, thinning skin, increased body hair, tiredness, mood changes, menstrual changes, sexual changes.

Common side effects may include:

  • burning, itching, swelling, or irritation of treated skin;
  • dry or cracking skin;
  • redness or crusting around your hair follicles;
  • spider veins;
  • stretch marks, thinning skin;
  • rash or hives;
  • acne; or
  • temporary hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Clobex Shampoo (Clobetasol Propionate Shampoo)

SLIDESHOW

Types of Psoriasis: Medical Pictures and Treatments See Slideshow
Clobex Shampoo Professional Information

SIDE EFFECTS

In clinical trials with CLOBEX® Shampoo (clobetasol propionate shampoo) , the following adverse reactions have been reported: burning/stinging, pruritus, edema, folliculitis, acne, dry skin, irritant dermatitis, alopecia, urticaria, skin atrophy and telangiectasia.

The table below summarizes selected adverse events that occurred in at least 1% of subjects in the Phase 2 and 3 studies for scalp psoriasis.

Summary of Selected Adverse Events ≥ 1% by Body System

Body System Clobetasol
Propionate Shampoo
N=558
Vehicle Shampoo
N=127
Skin and Appendages 49 (8.8%) 28 (22.0%)
Discomfort Skin 26 (4.7%) 16 (12.6%)
Pruritus 3 (0.5%) 9 (7.1%)
Body As A Whole 33 (5.9%) 12 (9.4%)
Headache 10 (1.8%) 1 (0.8%)

The following additional local adverse reactions have been reported infrequently with other topical corticosteroids, and they may occur more frequently with the use of occlusive dressings, especially with higher potency corticosteroids. These reactions are listed in an approximately decreasing order of occurrence: hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, skin atrophy, striae, and miliaria.

Systemic absorption of topical corticosteroids has produced reversible HPA axis suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some patients.

Read the entire FDA prescribing information for Clobex Shampoo (Clobetasol Propionate Shampoo)

© Clobex Shampoo Patient Information is supplied by Cerner Multum, Inc. and Clobex Shampoo Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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