Clomid vs. Aromasin

Are Clomid and Aromasin the Same Thing?

Clomid (clomiphene citrate) and Aromasin (exemestane) both work to reduce the estrogen levels in the body, but the drugs have different uses. Aromasin is a type of antineoplastic (anticancer) agent called an aromatase inhibitor that inhibits estrogen production and is used to treat breast cancer in postmenopausal women. Aromasin is often given to women whose cancer has progressed even after taking tamoxifen (Nolvadex, Soltamox) for 2 to 3 years. Clomid is a nonsteroidal ovulatory stimulant used to treat ovulatory dysfunction and polycystic ovary syndrome in women who, after other reasons for pregnancy failure have been ruled out, desire pregnancy and follow additional instructions that make pregnancy more likely to occur with this drug use.

What Are Possible Side Effects of Clomid?

Common side effects of Clomid include:

What Are Possible Side Effects of Aromasin?

Common side effects of Aromasin include:

Tell your doctor if you have serious side effects of Aromasin including:

  • bone fractures,
  • mental/mood changes (such as depression, anxiety),
  • vaginal bleeding,
  • persistent nausea or vomiting,
  • unusual tiredness,
  • dark urine, or
  • yellowing eyes or skin.

What is Clomid?

Clomid (clomiphene citrate) is a nonsteroidal, ovulatory stimulant used to treat ovulatory dysfunction and polycystic ovary syndrome in women who, after other reasons for pregnancy failure have been ruled out, desire pregnancy and follow additional instructions that make pregnancy more likely to occur with this drug use (see below about dosage and use). In addition, these women and their sperm donors usually need to undergo a number of tests scheduled by their OB-GYN doctor before Clomid is started.

What is Aromasin?

Aromasin (exemestane) is an antineoplastic (anticancer) agent used to treat breast cancer in postmenopausal women. Aromasin is often given to women whose cancer has progressed even after taking tamoxifen (Nolvadex, Soltamox) for 2 to 3 years.

SLIDESHOW

Breast Cancer Awareness: Symptoms, Diagnosis, and Treatment See Slideshow

What Drugs Interact With Clomid?

Clomid may interact with other drugs.

What Drugs Interact With Aromasin?

Aromasin may interact with rifampin, rifabutin, rifapentine, St. John's wort, seizure medications, bosentan, dexamethasone, barbiturates, HIV medications, or medicines to treat narcolepsy.

How Should Clomid Be Taken?

Clomid is available in 50 mg tablets. Treatment of the selected patient should begin with a low dose, 50 mg daily (1 tablet) for 5 days; dose changes are made by the treating physician. The first dose should occur on the 5th day of the female's ovulatory cycle and then subsequent doses at about the same time of day for a total of 5 days. Patients should be familiar with their ovulatory cycle so that properly timed coitus and ovulation stimulated by the drug occur. Long term therapy (past 6 cycles) is not recommended to avoid possible increases in cancer risk. Clomid may interact with other drugs. Tell your doctor all medications and supplements you use.

How Should Aromasin Be Taken?

The recommended dose of Aromasin in early and advanced breast cancer is one 25 mg tablet once daily after a meal.

QUESTION

A lump in the breast is almost always cancer. See Answer
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References


Clomid Product Monograph.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/016131s026lbl.pdf


Pfizer. Aromasin Product Information.

https://www.aromasin.com

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