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Clozaril vs. Klonopin

Reviewed on 4/22/2019

Are Clozaril and Klonopin the Same Thing?

Clozaril (clozapine) and Klonopin (clonazepam) are used to treat different psychiatric disorders.

Clozaril is used to treat severe schizophrenia symptoms in people who have not responded to other medications. Clozaril is also used to help reduce the risk of suicidal behavior in people with schizophrenia or similar disorders.

Klonopin is prescribed for the treatment of anxiety and seizure disorders.

Clozaril is an antipsychotic medication and Klonopin is benzodiazepine.

Side effects of Clozaril and Klonopin that are similar include constipation, sleep problems, dry mouth, blurred vision, drowsiness, dizziness, or headache.

Side effects of Clozaril that are different from Klonopin include drooling (especially at night), increased sweating, weight gain, spinning sensation, or shaking (tremor).

Side effects of Klonopin that are different from Clozaril include weakness, unsteadiness, depression, loss of orientation, problems with thinking or memory, slurred speech, sore gums, runny nose, loss of appetite, ordiarrhea.

Both Clozaril and Klonopin may interact with alcohol, narcotics, barbiturates, antidepressants, or seizure medications.

Clozaril may also interact with other antipsychotic medications, armodafinil, modafinil, arsenic trioxide, bosentan, cimetidine, conivaptan, dexamethasone, nefazodone, imatinib, isoniazid, St. John's wort, tacrolimus, antibiotics, antifungals, anti-malaria medications, atropine, belladonna, clidinium, dicyclomine, scopolamine, heart or blood pressure medications, HIV/AIDS medications, medicines to prevent or treat nausea and vomiting, or migraine headache medicines.

Klonopin may also interact with other drugs that make you sleepy or slow your breathing (sleeping pills, prescription cough medicines, muscle relaxers, or medicines for anxiety).

Do not stop using Clozaril or Klonopin suddenly or you could have unpleasant withdrawal symptoms.

What Are Possible Side Effects of Clozaril?

Side effects of Clozaril include:

What Are Possible Side Effects of Klonopin?

  • drowsiness,
  • dizziness,
  • weakness,
  • unsteadiness,
  • depression,
  • loss of orientation,
  • headache,
  • sleep disturbances,
  • problems with thinking or memory,
  • slurred speech,
  • dry mouth,
  • sore gums,
  • runny nose,
  • loss of appetite,
  • diarrhea,
  • constipation, and
  • blurred vision.

What Is Clozaril?

Clozaril (clozapine) is an antipsychotic medication that is used to treat severe schizophrenia symptoms in people who have not responded to other medications. Clozaril is also used to help reduce the risk of suicidal behavior in people with schizophrenia or similar disorders.

What Is Klonopin?

Klonopin is a prescription medicine used alone or with other medicines to treat:

It is not known if Klonopin is safe or effective in treating panic disorder in children younger than 18 years old.

Klonopin is a federal controlled substance (C-IV) because it can be abused or lead to dependence.

Klonopin is a benzodiazepine medicine. Benzodiazepines can cause severe drowsiness, breathing problems (respiratory depression), coma, and death when taken with opioid medicines. Klonopin can make you sleepy or dizzy and can slow your thinking and motor skills. This may get better over time.

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What Drugs Interact With Clozaril?

Clozaril may interact with other medicines that can make you sleepy or slow your breathing (such as cold or allergy medicines, narcotic pain medicines, sleeping pills, muscle relaxers, and medicines for depression, seizure, anxiety), and heart or blood pressure medications. Clozaril may also interact with alcohol, other antipsychotic medications, armodafinil, modafinil, arsenic trioxide, bosentan, cimetidine, conivaptan, dexamethasone, nefazodone, imatinib, isoniazid, phenobarbital and other barbiturates, St. John's wort, tacrolimus, antibiotics, antifungals, anti-malaria medications, atropine, belladonna, clidinium, dicyclomine, scopolamine, heart or blood pressure medications, HIV/AIDS medications, medicines to prevent or treat nausea and vomiting, and migraine headache medicines.

What Drugs Interact With Klonopin?

Klonopin may interact with cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, medicine for depression or anxiety, antibiotics, antifungal medicines, antidepressants, and barbiturates.

Klonopin may also interact with propantheline, MAO inhibitors, or medicines to treat psychiatric disorders.

Do not stop using Klonopin without first talking to your doctor, even if you feel fine. You may have increased seizures or unpleasant withdrawal symptoms if you stop using Klonopin suddenly.

How Should Clozaril Be Taken?

For most patients, the recommended dose of Clozaril is 5 mg three times a day. Based on individual patient response, the dose may be increased to 10 mg three times a day. Use of Clozaril for periods longer than two or three weeks is not recommended.

How Should Klonopin Be Taken?

Klonopin topping Klonopin suddenly can cause serious problems. Stopping Klonopin suddenly can cause seizures that will not stop (status epilepticus).

Klonopin can cause abuse and dependence.

Do not stop taking Klonopin all of a sudden. Stopping Klonopin suddenly can cause seizures that do not stop, hearing or seeing things that are not there (hallucinations), shaking, and stomach and muscle cramps.

Talk to your healthcare provider about slowly stopping Klonopin to avoid withdrawal symptoms.

Physical dependence is not the same as drug addiction. Your healthcare provider can tell you more about the differences between physical dependence and drug addiction.

Take Klonopin exactly as your healthcare provider tells you. If you take Klonopin for seizures, your healthcare provider may change the dose until you are taking the right amount of medicine to control your symptoms.

Klonopin is available as a tablet.

Do not stop taking Klonopin without first talking to your healthcare provider. Stopping Klonopin suddenly can cause serious problems.

Klonopin tablets should be taken with water and swallowed whole.

If you take too much Klonopin, call your healthcare provider or local Poison Control Center right away.

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References
SOURCES:

HLS Therapeutics (USA), Inc. Clozaril Product Information.

http://clozaril.com/

FDA. Klonopin Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/017533s053,020813s009lbl.pdf
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