Clozaril vs. Seroquel

Are Clozaril and Seroquel the Same Thing?

Clozaril (clozapine) and Seroquel (quetiapine) are antipsychotic medications used to treat schizophrenia.

Clozaril is also used to help reduce the risk of suicidal behavior in people with schizophrenia or similar disorders.

Seroquel is also used to treat major depression and bipolar disorder.

Side effects of Clozaril and Seroquel that are similar include constipation, sleep problems, weight gain, dry mouth, drowsiness, dizziness, or headache.

Side effects of Clozaril that are different from Seroquel include drooling (especially at night), increased sweating, blurred vision, spinning sensation, or shaking (tremor).

Side effects of Seroquel that are different from Clozaril include mood or behavior changes, stomach pain, upset stomach, nausea, vomiting, lightheadedness, tiredness, sore throat, breast swelling or discharge, missed menstrual periods, or increased appetite.

Both Clozaril and Seroquel may interact with alcohol, antipsychotic medications, antidepressants, antibiotics, HIV/AIDS medications, anti-malaria medications, narcotics, antifungals, heart or blood pressure medications, St. John's wort, or seizure medications.

Clozaril may also interact with armodafinil, modafinil, arsenic trioxide, bosentan, cimetidine, conivaptan, dexamethasone, nefazodone, imatinib, isoniazid, barbiturates, tacrolimus, atropine, belladonna, clidinium, dicyclomine, scopolamine, medicines to prevent or treat nausea and vomiting, migraine headache medicines.

Seroquel may also interact with heart rhythm medicines, cancer medications, other drugs that make you sleepy or slow your breathing (sleeping pills, prescription cough medicines, muscle relaxers, or anxiety medicines), or tuberculosis medicines.

Do not stop using Clozaril suddenly or you could have unpleasant withdrawal symptoms.

What Are Possible Side Effects of Clozaril?

Side effects of Clozaril include:

  • dry mouth or throat
  • headache
  • blurred vision
  • drowsiness
  • dizziness
  • fatigue
  • loss of appetite
  • stomach pain
  • nausea
  • diarrhea
  • constipation
  • gas, or
  • muscle weakness.

What Are Possible Side Effects of Seroquel?

  • fever,
  • hot flashes,
  • sensitivity to heat,
  • sweating,
  • headache,
  • nervousness,
  • irritability,
  • nausea,
  • sleep problems (insomnia),
  • changes in appetite or changes in weight,
  • changes in menstrual perdiods,
  • and temporary hair loss.

What Is Clozaril?

Clozaril (clozapine) is an antipsychotic medication that is used to treat severe schizophrenia symptoms in people who have not responded to other medications. Clozaril is also used to help reduce the risk of suicidal behavior in people with schizophrenia or similar disorders.

What Is Seroquel?

Seroquel (quetiapine) is a psychotropic medication used to treat schizophrenia in adults and children who are at least 13 years old. Seroquel is also used in the treatment of major depression and bipolar disorder.

QUESTION

Schizophrenia is the most disabling mental illness. See Answer

What Drugs Interact With Clozaril?

Clozaril may interact with other medicines that can make you sleepy or slow your breathing (such as cold or allergy medicines, narcotic pain medicines, sleeping pills, muscle relaxers, and medicines for depression, seizure, anxiety), and heart or blood pressure medications. Clozaril may also interact with alcohol, other antipsychotic medications, armodafinil, modafinil, arsenic trioxide, bosentan, cimetidine, conivaptan, dexamethasone, nefazodone, imatinib, isoniazid, phenobarbital and other barbiturates, St. John's wort, tacrolimus, antibiotics, antifungals, anti-malaria medications, atropine, belladonna, clidinium, dicyclomine, scopolamine, heart or blood pressure medications, HIV/AIDS medications, medicines to prevent or treat nausea and vomiting, and migraine headache medicines.

What Drugs Interact With Seroquel?

Seroquel may interact with many different drugs. Tell your doctor all medications and supplements you use.

How Should Clozaril Be Taken?

For most patients, the recommended dose of Clozaril is 5 mg three times a day. Based on individual patient response, the dose may be increased to 10 mg three times a day. Use of Clozaril for periods longer than two or three weeks is not recommended.

How Should Seroquel Be Taken?

Dosing preparations are 25, 50, 100, 200, 300, and 400 mg tablets.

SLIDESHOW

Schizophrenia: Symptoms, Types, Causes, Treatment See Slideshow
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References
SOURCES:

HLS Therapeutics (USA), Inc. Clozaril Product Information.

http://clozaril.com/

AstraZeneca. Seroquel XR Drug Information.

https://www.seroquelxr.com/

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