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Allergic Skin Disorders

Picture of Photoallergic Reaction

Picture of Photoallergic Reaction

Photoallergic reaction: An allergic reaction caused by drugs in which ultraviolet exposure changes the structure of the drug so that it is seen by the body's immune system as an invader. The allergic response causes inflammation of the skin in the sun-exposed areas. These usually resemble eczema and are generally long-lasting. Many drugs in this family are topical drugs. Individuals with photoallergic reactions may initially complain of itching (pruritus). This is then followed by redness and possibly swelling and eruption of the involved area. Common photoallergic drugs include some sunscreens, antimicrobials, painkillers, chemotherapy drugs, and fragrances.

Image Source: Color Atlas & Synopsis of Pediatric Dermatology Kay Shou-Mei Kane, Jen Bissonette Ryder, Richard Allen Johnson, Howard P. Baden, Alexander Stratigos Copyright 2002 by The McGraw-Hill Companies. All rights reserved.

Text: Sun-Sensitive Drugs (Photosensitivity to Drugs).