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Last reviewed on RxList: 3/15/2013
Coly-Mycin Side Effects Center

Last reviewed on RxList 1/4/2016

Coly-Mycin M (colistimethate injection) is an antibiotic used to treat infections caused by bacteria. Coly-Mycin M is available in generic form. Common side effects of Coly-Mycin M include numbness or tingling in your hands or feet, dizziness, spinning feeling, itching, mild skin rash, or upset stomach.

For adults and pediatric patients, Coly-Mycin M Parenteral should be given in 2 to 4 divided doses at dose levels of 2.5 to 5 mg/kg per day for patients with normal renal function, depending on the severity of the infection. Coly-Mycin M may interact with amikacin, gentamicin, kanamycin, neomycin, netilmicin, polymyxin, streptomycin, or tobramycin. Tell your doctor all medications you use. During pregnancy, Coly-Mycin M should be used only if prescribed. It may harm a fetus. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

Our Coly-Mycin M (colistimethate injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Coly-Mycin Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • diarrhea that is watery or bloody;
  • fever;
  • urinating less than usual or not at all;
  • muscle weakness; or
  • trouble breathing.

Less serious side effects may include:

  • mild numbness or tingling in your hands or feet;
  • dizziness, spinning feeling;
  • itching, mild skin rash; or
  • upset stomach.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Coly-Mycin (Colistimethate Injection)

Coly-Mycin Professional Information


The following adverse reactions have been reported:

Gastrointestinal: gastrointestinal upset

Nervous System: tingling of extremities and tongue, slurred speech, dizziness, vertigo and paresthesia

Integumentary: generalized itching, urticaria and rash

Body as a Whole: fever

Laboratory Deviations: increased blood urea nitrogen (BUN), elevated creatinine and decreased creatinine clearance

Respiratory System: respiratory distress and apnea

Renal System: nephrotoxicity and decreased urine output

For medical advice about adverse reactions contact your medical professional. To report SUSPECTED ADVERSE REACTIONS, contact JHP at 1-866-923-2547 or MEDWATCH at 1800-FDA-1088 (1-800-332-1088) or

Read the entire FDA prescribing information for Coly-Mycin (Colistimethate Injection)

Related Resources for Coly-Mycin

© Coly-Mycin Patient Information is supplied by Cerner Multum, Inc. and Coly-Mycin Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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