Acetaminophen Chlorpheniramine Dextromethorphan

Reviewed on 8/19/2021

QUESTION

Which illness is known as a viral upper respiratory tract infection? See Answer

What Is Acetaminophen/Chlorpheniramine/Dextromethorphan Used For and How Does it Work?

Acetaminophen/chlorpheniramine/dextromethorphan is an over-the-counter (OTC) product used for the relief of cold and flu symptoms.

Acetaminophen/chlorpheniramine/dextromethorphan is available under the following different brand names: Children's Triaminic Flu, Cough & Fever, Children's Tylenol Plus Cough & Runny Nose, Coricidin HBP Maximum Strength Flu, Vicks Formula 44 Custom Care Cough & Cold PM, and St. Joseph Maximum Strength Flu.

What Are the Dosages of Acetaminophen/Chlorpheniramine/Dextromethorphan?

Dosages of Acetaminophen/Chlorpheniramine/Dextromethorphan:

Dosage Forms and Strengths

Tablet

  • 500mg/2mg/15mg

Dosage Considerations – Should be Given as Follows:

Relief of Cold and Flu Symptoms

  • Adults and children 12 years and older: 2 tablets orally every 6 hours; not to exceed 8 tabs/day

Dosage Modifications

  • Renal impairment: No dose adjustment is required
  • Mild-to-moderate hepatic impairment: No dose adjustment required
  • Severe hepatic impairment: Not recommended; based on the increased inherent risk of bleeding in patients with severe hepatic impairment

What Are Side Effects Associated with Using Acetaminophen/Chlorpheniramine/Dextromethorphan?

Common side effects of Acetaminophen/Chlorpheniramine/Dextromethorphan include:

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Acetaminophen/Chlorpheniramine/Dextromethorphan?

Severe interactions of acetaminophen_chlorpheniramine_dextromethorphan include:

Acetaminophen/chlorpheniramine/dextromethorphan has serious interactions with at least 38 different drugs.

Acetaminophen/chlorpheniramine/dextromethorphan has moderate interactions with at least 267 different drugs.

Acetaminophen/chlorpheniramine/dextromethorphan has mild interactions with at least 76 different drugs.

What Are Warnings and Precautions for Acetaminophen/Chlorpheniramine/Dextromethorphan?

Warnings

This medication contains acetaminophen/chlorpheniramine/dextromethorphan. Do not take Children's Triaminic Flu, Cough & Fever, Children's Tylenol Plus Cough & Runny Nose, Coricidin HBP Maximum Strength Flu, Vicks Formula 44 Custom Care Cough & Cold PM, or St. Joseph Maximum Strength Flu if you are allergic to acetaminophen/chlorpheniramine/dextromethorphan or any ingredients contained in this drug.

Contraindications

  • Contraindicated in documented hypersensitivity; asthma attacks, narrow-angle glaucoma, symptomatic prostate hypertrophy, bladder neck obstruction, and stenosing peptic ulcer; known G-6-PD deficiency
  • Chlorpheniramine may cause significant confusional symptoms; not for administration to children under 2 years of age
  • Acetaminophen hepatotoxicity is possible in chronic alcoholics following various dose levels; severe or recurrent pain or high or continued fever may indicate a serious illness; contained in many OTC products and combined use with these products may result in toxicity due to cumulative doses exceeding recommended maximum dose
  • Do not take dextromethorphan for persistent or chronic cough associated with smoking, asthma, or emphysema, or if it is accompanied by excessive phlegm unless directed by a healthcare provider; dextromethorphan may slow the breathing

Effects of Drug Abuse

  • No information is available.

Short-Term Effects

  • See "What Are Side Effects Associated with Using Acetaminophen/Chlorpheniramine/Dextromethorphan?"

Long-Term Effects

  • See "What Are Side Effects Associated with Using Acetaminophen/Chlorpheniramine/Dextromethorphan?"

Cautions

Pregnancy and Lactation

There is no information available regarding the use of acetaminophen/chlorpheniramine/dextromethorphan during pregnancy or while breastfeeding.

Pregnant or breastfeeding patients should seek the advice of a health professional before using over-the-counter (OTC) drugs.

SLIDESHOW

A Cold or The Flu? How to Tell the Difference See Slideshow
References
https://reference.medscape.com/drug/childrens-triaminic-flu-cough-fever-childrens-tylenol-plus-cough-runny-nose-acetaminophen-chlorpheniramine-dextromethorphan-999369#4

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