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Ascorbic Acid

  • Medical and Pharmacy Editor: John P. Cunha, DO, FACOEP
    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, is a U.S. board-certified Emergency Medicine Physician. Dr. Cunha's educational background includes a BS in Biology from Rutgers, the State University of New Jersey, and a DO from the Kansas City University of Medicine and Biosciences in Kansas City, MO. He completed residency training in Emergency Medicine at Newark Beth Israel Medical Center in Newark, New Jersey.

Brand Name: Cenolate, Vitamin C

Generic Name: Ascorbic Acid

Drug Class: Vitamins, Water-Soluble

What Is Ascorbic Acid and How Does It Work?

Ascorbic Acid (vitamin C) is used to prevent or treat low levels of vitamin C in people who do not get enough of the vitamin from their diets. Most people who eat a normal diet do not need extra ascorbic acid. Low levels of vitamin C can result in a condition called scurvy. Scurvy may cause symptoms such as rash, muscle weakness, joint pain, tiredness, or tooth loss.

Vitamin C plays an important role in the body. It is needed to maintain the health of skin, cartilage, teeth, bone, and blood vessels. It is also used to protect your body's cells from damage. It is known as an antioxidant.

Ascorbic Acid may also be used with other vitamins for a certain eye condition (macular degeneration).

Ascorbic Acid is available under the following different brand and other names: Cenolate, and Vitamin C.

Dosages of Ascorbic Acid:

Dosage Forms and Strengths

Tablets

  • 100mg
  • 250mg
  • 500mg
  • 1g

Chewable, Tablet

  • 100mg
  • 250mg
  • 500mg

Capsule, extended-release

Tablet, extended release

  • 500mg
  • 1000mg
  • 1500mg

Crystals

  • 120g
  • 480g

Granules

  • 100g
  • 500g
  • 1000g

Injectable solution

  • 250mg/mL
  • 500mg/mL

Oral solution

  • 100mg/mL

Powder effervescent

  • 150g

Powder, oral

  • 113mg
  • 120mg
  • 480mg

Water, oral

  • 500mg

Syrup, oral

  • 100mg/mL

Dosage Considerations – Should be Given as Follows:

Recommended Daily Allowance (RDA)

  • Males: 90 mg/day
  • Females: 75 mg/day
  • Pregnant: 85 mg/day; not to exceed 2000 mg/day (80 mg if under 18 years; not to exceed 1800 mg/day)
  • Nursing: 120 mg/day; not to exceed 2000 mg/day (115 mg if under 18 years old; not to exceed 1800 mg/day)
  • Children 0-6 months: 40 mg/day
  • Children 6-12 months: 50 mg/day
  • Children 1-3 years: 15 mg/day
  • Children 3-8 years: 25 mg/day
  • Children 8-13 years: 45 mg/day
  • Children 13-18 years: (male) 75 mg/day; (female) 65 mg/day
  • Upper limit, pediatric: 1-3 years: 400 mg/day; 4-8 years old: 600 mg/day; 9-13 years old: 1.2 g/day; 12-18 years old: 1.8 g/day

Urinary Acidification

  • Adults: 4-12 g/day orally/intravenously (IV) divided three or four times daily
  • Pediatric: 500 mg/day divided orally/intravenously (IV) three or four times daily

Macular Degeneration (Off-label)

  • 500 mg/day orally with other vitamins and minerals

What Are Side Effects Associated with Using Ascorbic Acid (Zovirax)?

Side effects of ascorbic acid include

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Ascorbic Acid?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Ascorbic Acid has no known severe interactions with other drugs.

Moderate interactions of ascorbic acid include:

Mild interactions of ascorbic acid include:

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

What Are Warnings and Precautions for Ascorbic Acid ( Vasostrict, ADH)?

Warnings

  • This medication contains ascorbic acid. Do not take Cenolate or Vitamin C if you are allergic to ascorbic acid or any ingredients contained in this drug.
  • Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

Contraindications

  • Hypersensitivity

Effects of Drug Abuse

  • None

Short-Term Effects

  • See "What Are Side Effects Associated with Using Ascorbic Acid?"

Long-Term Effects

  • See "What Are Side Effects Associated with Using Ascorbic Acid?"

Cautions

  • Renal impairment, G6PD deficiency (high doses).
  • Patients with history of kidney stones (renal calculi) should avoid taking excessive doses for extended periods of time.
  • Solutions exposed to air rapidly oxidized.
  • Patients with diabetes mellitus should not take excessive doses for extended periods of times.
  • Destroyed by sunlight.

Pregnancy and Lactation

  • Use of ascorbic acid is generally acceptable during pregnancy when the dose is within the Recommended Daily Allowance (RDA). Controlled studies in pregnant women show no evidence of fetal risk.
  • Use ascorbic acid with caution during pregnancy in doses exceeding the RDA recommendations, if benefits outweigh risks. Animal studies show risk and human studies are not available or neither animal nor human studies were done.
  • Ascorbic acid enters breast milk. Ascorbic acid use is compatible with breastfeeding.
Reviewed on 10/24/2017

SOURCES:
Medscape. Ascorbic Acid.
https://reference.medscape.com/drug/cenolate-vitamin-c-ascorbic-acid-344416
RXlist. Ascorbic Acid.
https://www.rxlist.com/ascorbic-acid-side-effects-drug-center.htm

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