Reviewed on 8/26/2021

What Is Biotin and How Does It Work?

Biotin is a vitamin B supplement. It occurs naturally in food such as liver, legumes, tomatoes, soybeans, and carrots.

B vitamin is a member of the water-soluble vitamin family, and contributes to several naturally occurring reactions in the body between various enzymes or carboxylases.

While biotin deficiency is extremely rare, it may cause dermatitis, brittle fingernails, diabetes, hair loss (alopecia), and perosis. Biotin is necessary for healthy skin, nails, and hair.

Biotin is available under the following different brand names: coenzyme R, vitamin H, Nail-ex, and Appearex.

Dosages of Biotin Should Be Given As Follows


  • 30 mcg per day
  • 35 mcg per day, if lactating. (See “Pregnancy and Lactation” section)


  • 5-6 mcg per day, infants (0-1 year old)
  • 8-12 mg per day, children (1-9 years old)
  • 20-25 mcg per day, adolescents (9-18 years old)

Dosage Considerations

There are no dosage considertaions for biotin.


Vitamin D Deficiency: How Much Vitamin D Is Enough? See Slideshow

What Are Side Effects Associated with Using Biotin?

Biotin is generally safe with no documented adverse effects.

What Other Drugs Interact with Biotin?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

What Are Warnings and Precautions for Biotin?

This drug is generally safe and doses of 10 mg per day have been taken with no adverse effects.

This medication contains biotin. Do not take coenzyme R, vitamin H, Nail-ex or Appearex if you are allergic to biotin or any ingredients contained in this drug.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.


There are no contraindications associated with the use of biotin.

Effects of Drug Abuse

There are no effects of drug abuse associated with the use of biotin.

Short-Term Effects

There are no short-term effects associated with the use of biotin.

Long-Term Effects

There are no long-term effects associated with the use of biotin.


Hypersensitive individuals use with caution. Avoid consuming too much raw egg white as it contains protein which binds biotin.

Pregnancy and Lactation

There are no studies for use when pregnant or lactating. Consult your physician.

Medscape. Biotin.

Health Solutions From Our Sponsors