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Capsaicin

Brand Name and Other Names: Capzasin P, Zostrix, Capzasin-HP, Axsain, No Pain-HP, Pain Doctor, Pain-X, Rid-A-Pain, Salonpas Hot, Trixaicin, Menthac

Generic Name: Capsaicin

Drug Class: Analgesics, Topical; TRPV1 Agonists, Topical

What Is Capsaicin Used For and How Does it Work?

Capsaicin topical is an over-the-counter (OTC) product used to treat musculoskeletal pain. Capsaicin topical is used off-label to treat diabetic neuropathy.

Capsaicin topical is available under the following different brand names: Capzasin P, Zostrix, Capzasin-HP, Axsain, No Pain-HP, Pain Doctor, Pain-X, Rid-A-Pain, Salonpas Hot, Trixaicin, and Menthac.

Dosages of Capsaicin:

Dosage Forms and Strengths

Topical Cream

  • 0.025%
  • 0.035%
  • 0.075%
  • 0.1%

Topical Gel

  • 0.025%

Topical Liquid

  • 0.025%

Dosage Considerations – Should be Given as Follows:

Skeletomuscular Pain

  • Apply to affected area three or four times daily for 3-4 consecutive weeks and evaluate efficacy; efficacy decreased if used less than 3 times daily; not to exceed 4 applications/day; wash hands with soap and water after applying

Diabetic Neuropathy (Off-label)

  • Cream: Apply to affected area three or four times daily for 3-4 consecutive weeks and evaluate efficacy; not to exceed 4 applications/day; wash hands with soap and water after applying

Safety and efficacy not established in pediatric patients.

SLIDESHOW

Back Pain: 16 Back Pain Truths and Myths See Slideshow

What Are Side Effects Associated with Using Capsaicin?

Common side effects of Capsaicin include:

Less common side effects of capsaicin topical include:

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Capsaicin?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Capsaicin topical has no listed severe interactions with other drugs.

Capsaicin topical has no listed serious interactions with other drugs.

Capsaicin topical has no listed moderate interactions with other drugs.

Capsaicin topical has no listed mild interactions with other drugs.

What Are Warnings and Precautions for Capsaicin?

Warnings

This medication contains capsaicin topical. Do not take Capzasin P, Zostrix, Capzasin-HP, Axsain, No Pain-HP, Pain Doctor, Pain-X, Rid-A-Pain, Salonpas Hot, Trixaicin, or Menthac if you are allergic to capsaicin topical or any ingredients contained in this drug.

Contraindications

  • Hypersensitivity

Effects of Drug Abuse

  • No information available.

Short-Term Effects

  • See "What Are Side Effects Associated with Using Capsaicin?"

Long-Term Effects

  • See "What Are Side Effects Associated with Using Capsaicin?"

Cautions

  • For external use only
  • Do not apply to broken skin
  • Do not apply to face or scalp to avoid exposure to eyes or mucous membranes
  • Treated area may be sensitive to heat for several days (e.g., hot water, direct sunlight, vigorous exercise)
  • Use caution in patients with uncontrolled hypertension, history of cerebrovascular events

Pregnancy and Lactation

Capsaicin topical may be acceptable for use during pregnancy. Either animal studies show no risk but human studies are not available or animal studies showed minor risks and human studies were done and showed no risk.

It is unknown whether capsaicin topical is distributed in breast milk. Do not apply capsaicin topical to the nipple or areola. Consult your doctor before breastfeeding.

QUESTION

Medically speaking, the term "myalgia" refers to what type of pain? See Answer
Reviewed on 1/13/2020
References
https://reference.medscape.com/drug/capzasin-p-zostrix-capsaicin-topical-999316
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