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Cefaclor

  • Medical and Pharmacy Editor: John P. Cunha, DO, FACOEP
    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, is a U.S. board-certified Emergency Medicine Physician. Dr. Cunha's educational background includes a BS in Biology from Rutgers, the State University of New Jersey, and a DO from the Kansas City University of Medicine and Biosciences in Kansas City, MO. He completed residency training in Emergency Medicine at Newark Beth Israel Medical Center in Newark, New Jersey.

Brand Name: Ceclor, Raniclor

Generic Name: Cefaclor

Drug Class: Cephalosporins, 2nd Generation

What Is Cefaclor and How Does It Work?

Cefaclor is a prescription medication which is a cephalosporin-type antibiotic used to treat a wide variety of bacterial infections (middle ear, skin, urine and respiratory tract infections). It works by stopping the growth of bacteria.

Cefaclor only treats bacterial infections. It will not work for viral infections (common cold or the flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.

Cefaclor is available under the following different brand names: Ceclor and Raniclor.

Dosage of Cefaclor:

Adult, Pediatric and Geriatric:

Capsule

  • 250 mg
  • 500 mg

Dosing Considerations – Should be Given as Follows:

Infections

Adult and geriatric dosage:

  • 250-500 mg orally every 8 hours

Pediatric:

  • Infants less than 1 month old: safety and efficacy not established
  • Infants older than 1 month: 20-40 mg/kg/day orally divided every 8 hours; not to exceed 1 gram/day

Renal Impairment

  • Creatinine clearance: 10-50 ml/ min: half to full dose
  • Creatinine clearance: under 10 ml/min: half dose

Other Indications and uses:

SLIDESHOW

Fungus Among Us: What to Know About Fungal Infections in Pictures See Slideshow

What Are Side Effects Associated with Using Cefaclor?

Common Side effects of Cefaclor include:

Rare side effects of cefaclor include:

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Cefaclor?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Cefaclor has no known severe interactions with other drugs.

Serious interactions of cefaclor include:

  • BCG vaccine live
  • cholear vaccine
  • typhoid vaccine live

Moderate interactions of cefaclor include:

Mild interactions of cefaclor include:

This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.

QUESTION

Bowel regularity means a bowel movement every day. See Answer

What Are Warnings and Precautions for Cefaclor?

Warnings

  • This medication contains cefaclor. Do not take Ceclor or Raniclor if you are allergic to cefaclor or any ingredients contained in this drug
  • Keep out of reach of children
  • In case of overdose, get medical help or contact a Poison Control Center immediately

Contraindications

  • Documented hypersensitivity

Effects of Drug Abuse

  • No information available

Short-Term Effects

  • See "What Are Side Effects Associated with Using Cefaclor?"

Long-Term Effects

  • Bacterial or fungal overgrowth of non-susceptible organisms may occur with prolonged or repeated therapy
  • See "What Are Side Effects Associated with Using Cefaclor?"

Cautions

  • Safety and efficacy of extended release tablets not established in children younger than 16 years of age
  • Reduce dosage by 1/2 if creatinine clearance is 10-30 mL/min, and by 3/4 if under 10 mL/min (high doses may cause central nervous system toxicity). Bacterial or fungal overgrowth of non-susceptible organisms may occur with prolonged or repeated therapy

Pregnancy and Lactation

  • Use of cefaclor during pregnancy may be acceptable
  • Either animal studies show no risk but human studies are not available or animal studies showed minor risks and human studies were done and showed no risk
  • Cefaclor enters breast milk; use with caution if breastfeeding

Medscape. Cefaclor.
https://reference.medscape.com/drug/ceclor-raniclor-cefaclor-342494#0
RxList. Raniclor.
https://www.rxlist.com/cefaclor-drug.htm

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