Resorcinol/Sulfur

Reviewed on 9/23/2021

What Is Resorcinol/Sulfur and How Does It Work?

Resorcinol/sulfur is an over-the-counter (OTC) product used for acne vulgaris.

Resorcinol/sulfur is available under the following different brand names: Acnotex, Clearasil Stay Clear Acne Treatment Cream, Clearasil Adult Tinted Acne Treatment Cream, Rezamid, Glytone Flesh Tinted Acne Treatment Lotion, and Pernox Scrub for Oily Skin.

Dosages of Resorcinol/Sulfur

Dosage Forms and Strengths

Topical

  • 2%/4%
  • 2%/5%
  • 2%/8%

Dosage Considerations – Should be Given as Follows:

Acne Vulgaris

  • Adults and adolescents: After cleansing, apply sparingly to affected area(s) up to three times daily
  • Product content varies, check individual labeling

What Are Side Effects Associated with Using Resorcinol/Sulfur?

Side effects of resorcinol/sulfur include:

  • Skin redness
  • Excessive peeling
  • Skin irritation/inflammation

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Resorcinol/Sulfur?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

  • Resorcinol/sulfur has no listed severe interactions with other drugs.
  • Resorcinol/sulfur has no listed serious interactions with other drugs.
  • Resorcinol/sulfur has no listed moderate interactions with other drugs.
  • Resorcinol/sulfur has no listed mild interactions with other drugs.
     

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

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What Are Warnings and Precautions for Resorcinol/Sulfur? 

Warnings
 

This medication contains resorcinol/sulfur. Do not take Acnotex, Clearasil Stay Clear Acne Treatment Cream, Clearasil Adult Tinted Acne Treatment Cream, Rezamid, Glytone Flesh Tinted Acne Treatment Lotion, or Pernox Scrub for Oily Skin if you are allergic to resorcinol/sulfur or any ingredients contained in this drug.


Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

Contraindications

  • Hypersensitivity
  • Existing skin rash or irritation

Effects of Drug Abuse

  • No information available

Short-Term Effects

  • See "What Are Side Effects Associated with Using Resorcinol/Sulfur?”

Long-Term Effects

  • See "What Are Side Effects Associated with Using Resorcinol/Sulfur?”

Cautions

  • External use only
  • Discontinue if excessive skin irritation develops

Pregnancy and Lactation

Use resorcinol/sulfur with caution during pregnancy if benefits outweigh risks. Animal studies show risk and human studies are not available or neither animal nor human studies were done.

There is insufficient data regarding use of resorcinol/sulfur in lactating women. Resorcinol/sulfur is absorbed through intact and broken skin.

Pregnant or breastfeeding patients should seek advice of a health professional before using over-the-counter (OTC) drugs.

References
https://reference.medscape.com/drug/acnotex-resorcinol-sulfur-999345

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