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Medical and Pharmacy Editor:

Brand Name: Cortone

Generic Name: Cortisone

Drug Class: Corticosteroids

What Is Cortisone and How Does It Work?

Cortisone is a prescription drug and is a corticosteroid hormone (glucocorticoid). It decreases your body's natural defensive response and reduces symptoms such as swelling and allergic-type reactions.

Cortisone is used to treat conditions such as arthritis, blood/hormone/immune system disorders, allergic reactions, certain skin and eye conditions, breathing problems, and certain cancers.

Dosage of Cortisone:

Adult and Pediatric Dosages:


  • 5 mg
  • 10 mg
  • 25 mg

Dosing Considerations – Should be Given as Follows:



  • 2.5 mg/kg/day orally divided every 8 hours or 25-300 mg/day orally each day or divided every 12 hours
  • 1-5 mg/kg intramuscularly each day


  • 2.5 mg-10 mg/kg/day orally or 20-300 mg/m2/day orally divided every 6-8 hours

Physiologic Replacement


  • 0.5-0.75 mg/kg/day orally divided every 8 hours or 25-35 mg/day
  • 0.25-0.35 mg/kg intramuscularly each day


  • 0.5-0.75 mg/kg/day orally or 20-25 mg/sq.meter/day orally divided every 8 hours
Medically Reviewed by a Doctor on 6/9/2017

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