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Dextroamphetamine

Brand Name: Dexedrine, ProCentra, Zenzedi

Generic Name: Dextroamphetamine

Drug Class:Stimulants; ADHD Agents

What Is Dextroamphetamine and How Does It Work?

Dextroamphetamine is an amphetamine for the treatment of narcolepsy. Zenzedi is also indicated as a treatment for attention deficit hyperactivity disorder (ADHD) in pediatric patients ages 3 to 16 years as an integral part of a total treatment program for ADHD that may include counseling or other therapies.

Dextroamphetamine is available under the following different brand names: Dexedrine, ProCentra, and Zenzedi.

Dosages of Dextroamphetamine:

Adult and Pediatric Dosage Forms and Strengths

Capsule, extended-release (Dexedrine): Schedule II

  • 5mg
  • 10mg
  • 15mg

Tablet, immediate-release (Zenzedi): Schedule II

  • 2.5mg
  • 5mg
  • 7.5mg
  • 10mg
  • 15mg
  • 20mg
  • 30mg

Oral solution (ProCentra): Schedule II

  • 5mg/5mL

Dosage Considerations – Should be Given as Follows:

Narcolepsy

Adult: 10 mg/day orally; may titrate every week until side effects appear

Not to exceed 60 mg/day

Children over 12 years: 10 mg orally once/day initially; may increase by 10 mg once/week to optimal response

Geriatric: 5 mg/day orally; may increase the dose by 5 mg/day every week until side effects appear

Not to exceed 60 mg/day

Start at lowest dose

Attention Deficit Hyperactivity Disorder

Adult: 5 mg orally once or twice daily (4-6 hours apart); may increase 5 mg/day once/week until optimal response

Rarely necessary to exceed 40 mg/day

Pediatric:

Children under 3 years: Safety and efficacy not established

Children 3-5 years

  • Initial: 2.5 mg orally once/day; may increase by 2.5 mg/day once/week

Children 6 years and older

  • Initial: 5 mg orally once or twice daily (4-6 hours apart); may increase by 5 mg/day once/week until optimal response
  • Maintenance: 5-15 mg orally every 12 hours OR 5-10 mg orally every 8 hours
  • May substitute with once/day dosing of extended-release capsules
  • Rarely necessary to exceed 40 mg/day
Medically Reviewed by a Doctor on 11/7/2017



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