Dicloxacillin

Reviewed on 1/14/2022

Brand Name: N/A

Generic Name: Dicloxacillin

Drug Class: Penicillins, Penicillinase-Resistant

What Is Dicloxacillin and How Does It Work?

Dicloxacillin is a prescription medication used to treat bacterial infections caused by Staphylococcus aureus.

  • Dicloxacillin is available under the following different brand names:

What Are Dosages of Dicloxacillin?

Adult and pediatric dosage

Capsule

  • 250mg
  • 500mg

Infections

Adult dosage

  • 125-500 mg orally every 6 hours
  • Take on an empty stomach

Pediatric dosage

  • Children weighing less than 40 kg: 12.5-25 mg/kg/day orally divided every 6 hours
  • Severe infection: 50-100 mg/kg/day orally divided every 6 hours
  • Children weighing 40 kg or more: 125-500 mg orally every 6 hours
  • Take on an empty stomach

Dosage Considerations – Should be Given as Follows: 

  • See “Dosages”.

What Are Side Effects Associated with Using Dicloxacillin?

Common side effects of Dicloxacillin include:

Serious side effects of Dicloxacillin include:

Rare side effects of Dicloxacillin include:

  • none 
This is not a complete list of side effects and other serious side effects or health problems may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

QUESTION

Bowel regularity means a bowel movement every day. See Answer

What Other Drugs Interact with Dicloxacillin?

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first

  • Dicloxacillin has severe interactions with no other drugs.
  • Dicloxacillin has serious interactions with the following drugs:
  • Dicloxacillin has moderate interactions with at least 31 other drugs.
  • Dicloxacillin has minor interactions with at least 11 other drugs.

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this drug, tell your doctor or pharmacist of all the drugs you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

What Are Warnings and Precautions for Dicloxacillin?

Contraindications

  • Hypersensitivity to penicillins, cephalosporins, imipenem
  • Initial treatment of severe infections
  • Concomitant live bacterial vaccines

Effects of drug abuse

  • None

Short-Term Effects

  • See “What Are Side Effects Associated with Using Dicloxacillin?”

Long-Term Effects

  • See “What Are Side Effects Associated with Using Dicloxacillin?”

Cautions

  • Monitor PT inpatient is taking warfarin concurrently
  • Prolonged use may result in superinfection
  • Elimination of drugs in neonates is slow; use caution

Pregnancy and Lactation

  • Use may be acceptable in pregnancy. 
  • Lactation: excreted in breast milk, use caution
References
Medscape. Dicloxacillin.

https://reference.medscape.com/drug/dicloxacillin-342477

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