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Medical and Pharmacy Editor:

Brand Name: Vibramycin, Monodox, Acticlate, Atridox, Avidoxy, Doxy, Doxycin, Doryx, Oracea, Periostat, Adoxa, Ocudox, Doryx MPC

Generic Name: doxycycline

Drug Class: Tetracyclines

What Is Doxycycline and How Does It Work?

Doxycycline is a prescription antibiotic medication indicated for the treatment of the following infections and diseases: Rocky Mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers, respiratory tract infections, urinary tract infections. lymphogranuloma venereum, psittacosis (ornithosis), trachoma, inclusion conjunctivitis, uncomplicated urethral/endocervical/rectal infections in adults, nongonococcal urethritis, relapsing fever, chancroid, plague, tularemia, cholera, campylobacter fetus, brucellosis, bartonellosis, granuloma inguinale, Escherichia coli, enterobacter aerogenes, Shigella species, Acinetobacter species, anthrax, Uncomplicated gonorrhea, Syphilis, Yaws, Listeriosis, Vincent's infection, Actinomycosis, and infections caused by Clostridium species.

In acute intestinal amebiasis, doxycycline may be a useful adjunct to amebicides.

In severe acne, doxycycline may be useful adjunctive therapy.

Because many strains of microorganisms have been shown to be resistant to doxycycline, culture and susceptibility testing are recommended.

Doxycycline is available under the following different brand names: Vibramycin, Monodox, Acticlate, Atridox, Avidoxy, Doxy, Doxycin, Doryx, Oracea, Periostat, Adoxa, Ocudox, and Doryx MPC.

Dosages of Doxycycline Should Be Given As Follows:

Adult Dosage Forms & Strengths


  • 50 mg (Monodox, generic)
  • 75 mg (Monodox)
  • 100 mg (Monodox, Vibramycin, generic)
  • 150 mg (Adoxa)

Solution, reconstituted powder for IV

  • 100 mg (Doxy, generic)


  • 50 mg/5 mL (Vibramycin)

Oral Suspension

  • 25 mg/ 5mL (Vibramycin, generic)


  • 20mg (generic)
  • 50mg (Adoxa, generic)
  • 75mg (Acticlate, Adoxa, generic)
  • 100mg (Adoxa, generic)
  • 150mg (Acticlate, generic)

Tablet, delayed-release

  • 50mg (Doryx)
  • 60mg (Doryx MPC)
  • 75mg (generic)
  • 100mg (generic)
  • 120mg (Doryx MPC)
  • 150mg (Doryx, generic)
  • 200mg (Doryx)

Capsule, delayed-release

  • 40 mg (Oracea, generic)

Periodontal extended-release liquid

  • 10%

Dosage Considerations – Should be Given as Follows:

General Dosage

Initial: 200 mg/day divided twice daily orally/intravenously (IV) on first day (IV may be given once/day), THEN

Maintenance: 100-200 mg/day once/day or divided once every 12 hours orally/intravenously (IV) (IV may be given once/day)

Specific dosing varies depending on the condition being treated; consult your doctor.

Dosage Considerations

Propionibacterium acnes, Actinomyces israelii, Acinetobacter spp, Bacillus anthracis, Bacteroides spp., Bartonella bacilliformis, Bartonella henselae, Bartonella quintana, Borrelia recurrentis, Brucella spp, Campylobacter jejuni, Chlamydia psittaci, Chlamydia trachomatis, Capnocytophaga canimorsus, Citrobacter diversus, Citrobacter freundii, Escherichia coli, Eikenella corrodens, Francisella tularensis, Haemophilus ducreyi, Helicobacter pylori, Klebsiella granulomatis, Klebsiella pneumoniae, Listeria monocytogenes, Mycoplasma hominis, Mycoplasma pneumoniae, Neisseria gonorrhoeae, Propionibacterium acnes, Rickettsiae, Shigella spp., MRSA, Staphylococcus saprophyticus, Streptococcus spp, Treponema pallidum, Ureaplasma urealyticum, Vibrio cholerae, Yersinia enterocolitica, Yersinia pestis, VRE, mycobacteria other than tuberculosis

Medically Reviewed by a Doctor on 4/14/2017

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