Antipyrine Benzocaine Phenylephrine

Reviewed on 8/23/2021

What Is Antipyrine/Benzocaine/Phenylephrine Used For and How Does it Work?

Antipyrine/benzocaine/phenylephrine is an over-the-counter (OTC) product used to relieve ear pain/congestion.

Antipyrine/benzocaine/phenylephrine is available under the following different brand names: EarGesic and Otogesic.

What Are the Dosages of Antipyrine/Benzocaine/Phenylephrine?

Dosages of Antipyrine/Benzocaine/Phenylephrine:

Dosage Forms and Strengths

Otic Solution

  • 5%/5%/0.25%

Dosage Considerations – Should be Given as Follows:

Ear Pain/Congestion

  • Apply to the ear canal (drop by drop) until ear canal filled, insert gauze into ear-opening; may apply three times daily for two to three days

QUESTION

Ear infection or acute otitis media is an infection of the middle ear. See Answer

What Are Side Effects Associated with Using Antipyrine/Benzocaine/Phenylephrine?

Common side effects of acetaminophen/aspirin include:

  • Temporary stinging/burning in the ear canal
  • Local hypersensitivity reaction

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Antipyrine/Benzocaine/Phenylephrine?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

  • Antipyrine/benzocaine/phenylephrine has no listed severe interactions with other drugs.
  • Antipyrine/benzocaine/phenylephrine has no listed serious interactions with other drugs.
  • Antipyrine/benzocaine/phenylephrine has no listed moderate interactions with other drugs.
  • Antipyrine/benzocaine/phenylephrine has no listed mild interactions with other drugs.

What Are Warnings and Precautions for Antipyrine/Benzocaine/Phenylephrine?

Warnings

This medication contains antipyrine/benzocaine/phenylephrine. Do not take EarGesic or Otogesic if you are allergic to antipyrine/benzocaine/phenylephrine or any ingredients contained in this drug.

Contraindications

Effects of Drug Abuse

  • No information is available.

Short-Term Effects

  • See "What Are Side Effects Associated with Using Antipyrine/Benzocaine/Phenylephrine?"

Long-Term Effects

  • See "What Are Side Effects Associated with Using Antipyrine/Benzocaine/Phenylephrine?"

Cautions

  • Contact physician for severe pain/burning after instilling drops
  • Discontinue if rash, redness, or dry skin develops

Pregnancy and Lactation

  • Use antipyrine/benzocaine/phenylephrine with caution during pregnancy if the benefits outweigh the risks. Animal studies show risk and human studies are not available or neither animal nor human studies were done.
  • It is unknown if antipyrine/benzocaine/phenylephrine passes into breast milk.
  • Pregnant or breastfeeding patients should seek the advice of a health professional before using over-the-counter (OTC) drugs.
References
https://reference.medscape.com/drug/eargesic-antipyrine-benzocaine-phenylephrine-999343

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