Apaziquone

Reviewed on 8/23/2021

What Is Apaziquone Used For and How Does it Work?

Apaziquone is currently in clinical trials for intravesical instillation post-transurethral resection of bladder tumors (post-TURBT) in patients with non-muscle invasive bladder cancer (NMIBC).

Apaziquone is available under the following different brand names: Eoquin, Neoquin, and Qapzola.

What Are the Dosages of Apaziquone?

Dosages of Apaziquone:

  • 4 mg in 40 mL diluent

Dosage Considerations – Should be Given as Follows:

  • The proposed clinical dose of apaziquone is a single 4 mg dose, administered intravesically in a volume of 40 mL (0.1 mg/mL) of diluent that is instilled into the bladder 30 minutes post-TURBT and retained in the bladder for a period of 1 hour

SLIDESHOW

Signs of Prostate Cancer: Symptoms, PSA Test, Treatments See Slideshow

What Are Side Effects Associated with Using Apaziquone?

Side effects of Apaziquone include:

Serious side effects of Apaziquone include:

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Apaziquone?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

  • Apaziquone has no listed severe interactions with other drugs.
  • Apaziquone has no listed serious interactions with other drugs.
  • Apaziquone has no listed moderate interactions with other drugs.
  • Apaziquone has no listed mild interactions with other drugs.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

What Are Warnings and Precautions for Apaziquone?

Warnings

This medication contains Apaziquone. Do not take Eoquin, Neoquin, or Qapzola if you are allergic to apaziquone or any ingredients contained in this drug.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

Contraindications

  • No information is available.

Effects of Drug Abuse

  • No information is available.

Short-Term Effects

  • See "What Are Side Effects Associated with Using Apaziquone?"

Long-Term Effects

  • See "What Are Side Effects Associated with Using Apaziquone?"

Cautions

  • No information is available.

Pregnancy and Lactation

  • Apaziquone is still in clinical trials. There is no information available regarding the use of apaziquone during pregnancy or while breastfeeding. Consult your doctor.
References
https://www.fda.gov/media/100414/download

https://www.cancer.gov/publications/dictionaries/cancer-drug/def/apaziquone

Health Solutions From Our Sponsors